Multivariate Data Exploration Through Coordinated Views | IEEE Journals & Magazine | IEEE Xplore

Multivariate Data Exploration Through Coordinated Views


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A demonstration of some of CroP's dynamic visualization models and data analysis methods being used in the discovery of patterns in a gene expression time-series dataset ...

Abstract:

Many fields of study still face the challenges inherent to the analysis of complex multidimensional datasets, such as the field of computational biology, whose research o...Show More

Abstract:

Many fields of study still face the challenges inherent to the analysis of complex multidimensional datasets, such as the field of computational biology, whose research of infectious diseases must contend with large protein-protein interaction networks with thousands of genes that vary in expression values over time. In this paper, we explore the visualization of multivariate data through CroP, a data visualization tool with a coordinated multiple views framework where users can adapt the workspace to different problems through flexible panels. In particular, we focus on the visualization of relational and temporal data, the latter being represented through layouts that distort timelines to represent the fluctuations of values across complex datasets, creating visualizations that highlight significant events and patterns. Moreover, CroP provides various layouts and functionalities to not only highlight relationships between different variables, but also dig-down into discovered patterns in order to better understand their sources and their effects. These methods are demonstrated through multiple experiments with diverse multivariate datasets, with a focus on gene expression time-series datasets. In addition to a discussion of our results, we also validate CroP through model and interface tests performed with participants from both the fields of information visualization and computational biology.
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A demonstration of some of CroP's dynamic visualization models and data analysis methods being used in the discovery of patterns in a gene expression time-series dataset ...
Published in: IEEE Access ( Volume: 10)
Page(s): 78788 - 78817
Date of Publication: 26 July 2022
Electronic ISSN: 2169-3536

Funding Agency:

Author image of António Cruz
Department of Informatics Engineering, Centre for Informatics and Systems of the University of Coimbra, University of Coimbra, Coimbra, Portugal
LASI—Intelligent Systems Associate Laboratory, Coimbra, Portugal
António Cruz is currently pursuing the Ph.D. degree with the Faculty of Sciences and Technology, University of Coimbra, through the Doctoral Program for Information Science and Technology. His early visualization work was later published in IEEE Computer Graphics and Applications. During his M.Sc. degree, he has developed a visualization tool for genetic algorithms, which was published at GECCO. He is developing interacti...Show More
António Cruz is currently pursuing the Ph.D. degree with the Faculty of Sciences and Technology, University of Coimbra, through the Doctoral Program for Information Science and Technology. His early visualization work was later published in IEEE Computer Graphics and Applications. During his M.Sc. degree, he has developed a visualization tool for genetic algorithms, which was published at GECCO. He is developing interacti...View more
Author image of Joel P. Arrais
Department of Informatics Engineering, Centre for Informatics and Systems of the University of Coimbra, University of Coimbra, Coimbra, Portugal
LASI—Intelligent Systems Associate Laboratory, Coimbra, Portugal
Joel P. Arrais received the M.Sc. and Ph.D. degrees in computer science from the University of Aveiro, in 2004 and 2010, respectively. He has been an Assistant Professor at the Department of Informatics Engineering, University of Coimbra, since 2012. In the recent past, he has been involved on several studies that focused on the analysis and knowledge extraction from gene-expression data. He has authored about 100 works, ...Show More
Joel P. Arrais received the M.Sc. and Ph.D. degrees in computer science from the University of Aveiro, in 2004 and 2010, respectively. He has been an Assistant Professor at the Department of Informatics Engineering, University of Coimbra, since 2012. In the recent past, he has been involved on several studies that focused on the analysis and knowledge extraction from gene-expression data. He has authored about 100 works, ...View more
Author image of Penousal Machado
Department of Informatics Engineering, Centre for Informatics and Systems of the University of Coimbra, University of Coimbra, Coimbra, Portugal
LASI—Intelligent Systems Associate Laboratory, Coimbra, Portugal
Penousal Machado is currently an Associate Professor at the Department of Informatics Engineering, University of Coimbra. He is a Coordinator of the Cognitive and Media Systems Group, CISUC. He is the author of more than 200 refereed journals and conference papers. His research interests include artificial intelligence, evolutionary computation, computational creativity, and information visualization. He is the President ...Show More
Penousal Machado is currently an Associate Professor at the Department of Informatics Engineering, University of Coimbra. He is a Coordinator of the Cognitive and Media Systems Group, CISUC. He is the author of more than 200 refereed journals and conference papers. His research interests include artificial intelligence, evolutionary computation, computational creativity, and information visualization. He is the President ...View more

Author image of António Cruz
Department of Informatics Engineering, Centre for Informatics and Systems of the University of Coimbra, University of Coimbra, Coimbra, Portugal
LASI—Intelligent Systems Associate Laboratory, Coimbra, Portugal
António Cruz is currently pursuing the Ph.D. degree with the Faculty of Sciences and Technology, University of Coimbra, through the Doctoral Program for Information Science and Technology. His early visualization work was later published in IEEE Computer Graphics and Applications. During his M.Sc. degree, he has developed a visualization tool for genetic algorithms, which was published at GECCO. He is developing interactive visualization models directed at exploring large and complex datasets within the field of computational biology, including gene expression time-series, biological pathways, and protein-protein interaction networks. His research interests include graphic design and programming applied to information visualization, in particular the development of dynamic data visualization methods and tools.
António Cruz is currently pursuing the Ph.D. degree with the Faculty of Sciences and Technology, University of Coimbra, through the Doctoral Program for Information Science and Technology. His early visualization work was later published in IEEE Computer Graphics and Applications. During his M.Sc. degree, he has developed a visualization tool for genetic algorithms, which was published at GECCO. He is developing interactive visualization models directed at exploring large and complex datasets within the field of computational biology, including gene expression time-series, biological pathways, and protein-protein interaction networks. His research interests include graphic design and programming applied to information visualization, in particular the development of dynamic data visualization methods and tools.View more
Author image of Joel P. Arrais
Department of Informatics Engineering, Centre for Informatics and Systems of the University of Coimbra, University of Coimbra, Coimbra, Portugal
LASI—Intelligent Systems Associate Laboratory, Coimbra, Portugal
Joel P. Arrais received the M.Sc. and Ph.D. degrees in computer science from the University of Aveiro, in 2004 and 2010, respectively. He has been an Assistant Professor at the Department of Informatics Engineering, University of Coimbra, since 2012. In the recent past, he has been involved on several studies that focused on the analysis and knowledge extraction from gene-expression data. He has authored about 100 works, including journals and conference papers, including participation on reference conferences (ISMB/ECCB, BIBE, ICANN, and ESANN) and journals (Bioinformatics (Oxford), IEEE/ACM Transactions on Computational Biology and Bioinformatics, and Journal of Cheminformatics). He has been involved in several national and FP7/HORIZON2020 European funded projects. His particular research interests include using pattern recognition and machine learning methods applied to biological problems.
Joel P. Arrais received the M.Sc. and Ph.D. degrees in computer science from the University of Aveiro, in 2004 and 2010, respectively. He has been an Assistant Professor at the Department of Informatics Engineering, University of Coimbra, since 2012. In the recent past, he has been involved on several studies that focused on the analysis and knowledge extraction from gene-expression data. He has authored about 100 works, including journals and conference papers, including participation on reference conferences (ISMB/ECCB, BIBE, ICANN, and ESANN) and journals (Bioinformatics (Oxford), IEEE/ACM Transactions on Computational Biology and Bioinformatics, and Journal of Cheminformatics). He has been involved in several national and FP7/HORIZON2020 European funded projects. His particular research interests include using pattern recognition and machine learning methods applied to biological problems.View more
Author image of Penousal Machado
Department of Informatics Engineering, Centre for Informatics and Systems of the University of Coimbra, University of Coimbra, Coimbra, Portugal
LASI—Intelligent Systems Associate Laboratory, Coimbra, Portugal
Penousal Machado is currently an Associate Professor at the Department of Informatics Engineering, University of Coimbra. He is a Coordinator of the Cognitive and Media Systems Group, CISUC. He is the author of more than 200 refereed journals and conference papers. His research interests include artificial intelligence, evolutionary computation, computational creativity, and information visualization. He is the President of SPECIES—the Society for the Promotion of Evolutionary Computation in Europe and its Surroundings. He is a member of the Steering Committee of EuroGP, EvoMUSART, and Evostar. He is a member of the Executive Board of SPECIES. He was a recipient of several scientific awards, including the prestigious EvoStar Award for Outstanding Contribution to Evolutionary Computation in Europe. His publications have been awarded as best papers multiple times. He has been a keynote speaker at several major international conferences. His work was presented in venues, such as the National Museum of Contemporary Art and MoMA, NY, USA. He has chaired major events, including ICCC, PPSN, EvoStar, EuroGP, and EvoMusart.
Penousal Machado is currently an Associate Professor at the Department of Informatics Engineering, University of Coimbra. He is a Coordinator of the Cognitive and Media Systems Group, CISUC. He is the author of more than 200 refereed journals and conference papers. His research interests include artificial intelligence, evolutionary computation, computational creativity, and information visualization. He is the President of SPECIES—the Society for the Promotion of Evolutionary Computation in Europe and its Surroundings. He is a member of the Steering Committee of EuroGP, EvoMUSART, and Evostar. He is a member of the Executive Board of SPECIES. He was a recipient of several scientific awards, including the prestigious EvoStar Award for Outstanding Contribution to Evolutionary Computation in Europe. His publications have been awarded as best papers multiple times. He has been a keynote speaker at several major international conferences. His work was presented in venues, such as the National Museum of Contemporary Art and MoMA, NY, USA. He has chaired major events, including ICCC, PPSN, EvoStar, EuroGP, and EvoMusart.View more

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