Imaging of Excised Breast Tumor Phantom using Automated Sub-Terahertz Waveguide Iris Probe System.
Impact Statement:Take-Home Messages •A non-invasive, robust, compact, and cost-effective electronic sub-terahertz waveguide iris probe for detecting tumor margins intraoperatively during ...Show More
Abstract:
In breast-conserving operations, terahertz imaging (THz) has become a popular method of assessing tumor margins intraoperatively. Typically, THz measurements are conducte...Show MoreMetadata
Impact Statement:
Take-Home Messages •A non-invasive, robust, compact, and cost-effective electronic sub-terahertz waveguide iris probe for detecting tumor margins intraoperatively during breast-conserving surgery has been demonstrated in the research. •Waveguide iris probe using sub-terahertz frequency bands enables detection of positive margins without the need to resect tissues using 100 μm lateral resolution and 1 mm sensing depth for fat surrounding healthy tissues, which has been demonstrated using breast tissue phantoms. •This work focuses on imaging of excised tumors in breast-conserving surgery using a non-invasive compact setup analyzing the margin of the breast tumor utilizing the difference in dielectric constant between the normal and malignant tissues. •The results reveal the effectiveness of sub-terahertz waves for tumor margin assessment applications, which require high resolution and tissue penetrating imaging techniques.
Abstract:
In breast-conserving operations, terahertz imaging (THz) has become a popular method of assessing tumor margins intraoperatively. Typically, THz measurements are conducted with electro-optical setups that penetrate tissue just a few microns deep. The study demonstrates a robust, efficient, and cost-effective electronic sub-THz waveguide probe for detecting tumor margins intraoperatively during lumpectomies. The proposed iris waveguide probe is capable of detecting fat, fibrous, and tumorous tissue in breast tissue. The device can identify both positive and negative margins in the frequency range of 110-170 GHz. The scanning probe can be used to rapidly and effectively depict the excised tissue surface by placing it in contact with it. According to the imaging results, this probe has a lateral sensitivity of 0.2 mm and a detection depth of 1 mm. It is manufactured using CNC micromachining technology to ensure easy and cost-effective production. The probe was designed and tested in HFSS ...
Imaging of Excised Breast Tumor Phantom using Automated Sub-Terahertz Waveguide Iris Probe System.
Published in: IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology ( Volume: 6, Issue: 3, September 2022)
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