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Attention Retrieval Model for Entity Relation Extraction From Biological Literature | IEEE Journals & Magazine | IEEE Xplore

Attention Retrieval Model for Entity Relation Extraction From Biological Literature


We present an alternative framework called the Attention Retrieval Model (ARM), which enhances the applicability of attention-based models compared to the regular classif...

Abstract:

Natural Language Processing (NLP) has contributed to extracting relationships among biological entities, such as genes, their mutations, proteins, diseases, processes, ph...Show More

Abstract:

Natural Language Processing (NLP) has contributed to extracting relationships among biological entities, such as genes, their mutations, proteins, diseases, processes, phenotypes, and drugs, for a comprehensive and concise understanding of information in the literature. Self-attention-based models for Relationship Extraction (RE) have played an increasingly important role in NLP. However, self-attention models for RE are framed as a classification problem, which limits its practical usability in several ways. We present an alternative framework called the Attention Retrieval Model (ARM), which enhances the applicability of attention-based models compared to the regular classification approach, for RE. Given a text sequence containing related entities/keywords, ARM learns the association between a chosen entity/keyword with the other entities present in the sequence, using an underlying self-attention mechanism. ARM provides a flexible framework for a modeller to customise their model, facilitate data integration, and integrate expert knowledge to provide a more practical approach for RE. ARM can extract unseen relationships that are not annotated in the training data, analogous to zero-shot learning. To sum up, ARM provides an alternative self-attention-based deep learning framework for RE, that can capture directed entity relationships.
We present an alternative framework called the Attention Retrieval Model (ARM), which enhances the applicability of attention-based models compared to the regular classif...
Published in: IEEE Access ( Volume: 10)
Page(s): 22429 - 22440
Date of Publication: 25 February 2022
Electronic ISSN: 2169-3536
Author image of Prashant Srivastava
Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany
Prashant Srivastava received the master’s degree in physics from the Indian Institute of Science Education and Research, Kolkata, and the master’s degree in data science and analytics from the Department of Computer Science, Royal Holloway, University of London. He is currently a Research Assistant with the Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Germany. His...Show More
Prashant Srivastava received the master’s degree in physics from the Indian Institute of Science Education and Research, Kolkata, and the master’s degree in data science and analytics from the Department of Computer Science, Royal Holloway, University of London. He is currently a Research Assistant with the Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Germany. His...View more
Author image of Saptarshi Bej
Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany
Leibniz-Institute for Food Systems Biology, Technical University of Munich, Freising, Germany
Saptarshi Bej received the master’s degree in mathematics from the Indian Institute of Science Education and Research, Kolkata, in 2014. He is currently a Research Associate at the Institute of Computer Science, University of Rostock, Germany, and a Guest Scientist with the Leibniz-Institute for Food Systems Biology, Technical University of Munich, Germany. His research interests include graph theory, specifically the Bar...Show More
Saptarshi Bej received the master’s degree in mathematics from the Indian Institute of Science Education and Research, Kolkata, in 2014. He is currently a Research Associate at the Institute of Computer Science, University of Rostock, Germany, and a Guest Scientist with the Leibniz-Institute for Food Systems Biology, Technical University of Munich, Germany. His research interests include graph theory, specifically the Bar...View more
Author image of Kristian Schultz
Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany
Kristian Schultz received the degrees in mathematics and computer science, in 2014. After that, he worked for two years in the field of discrete mathematics on Sperner families with the Department of Mathematics, University in Rostock, Germany. In between, he extended his software developing skills in industry. Since 2020, he returned to the Department of Systems Biology and Bioinformatics, University of Rostock, where he...Show More
Kristian Schultz received the degrees in mathematics and computer science, in 2014. After that, he worked for two years in the field of discrete mathematics on Sperner families with the Department of Mathematics, University in Rostock, Germany. In between, he extended his software developing skills in industry. Since 2020, he returned to the Department of Systems Biology and Bioinformatics, University of Rostock, where he...View more
Author image of Kristina Yordanova
Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany
Kristina Yordanova received the bachelor’s degree in computer engineering from the University of Duisburg-Essen, Germany, in 2008, the master’s degree in artificial intelligence from Maastricht University, The Netherlands, in 2009, and the Ph.D. degree in ubiquitous computing from the University of Rostock, Germany, in 2014. She is currently the Head of the Junior Research Group “Cognitive Methods for Situation-Aware Assi...Show More
Kristina Yordanova received the bachelor’s degree in computer engineering from the University of Duisburg-Essen, Germany, in 2008, the master’s degree in artificial intelligence from Maastricht University, The Netherlands, in 2009, and the Ph.D. degree in ubiquitous computing from the University of Rostock, Germany, in 2014. She is currently the Head of the Junior Research Group “Cognitive Methods for Situation-Aware Assi...View more
Author image of Olaf Wolkenhauer
Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany
Leibniz-Institute for Food Systems Biology, Technical University of Munich, Freising, Germany
Olaf Wolkenhauer received the degrees in systems and control engineering and the Ph.D. degree for research in possibility theory with applications to data analysis. He spent over ten years at the University of Manchester Institute of Science and Technology, U.K. In 2003, he was appointed as a Professor of systems biology and bioinformatics at the University of Rostock, Germany. In 2005, he became a fellow of the Stellenbo...Show More
Olaf Wolkenhauer received the degrees in systems and control engineering and the Ph.D. degree for research in possibility theory with applications to data analysis. He spent over ten years at the University of Manchester Institute of Science and Technology, U.K. In 2003, he was appointed as a Professor of systems biology and bioinformatics at the University of Rostock, Germany. In 2005, he became a fellow of the Stellenbo...View more

Author image of Prashant Srivastava
Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany
Prashant Srivastava received the master’s degree in physics from the Indian Institute of Science Education and Research, Kolkata, and the master’s degree in data science and analytics from the Department of Computer Science, Royal Holloway, University of London. He is currently a Research Assistant with the Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Germany. His current research interests include algorithm development and their applications in literature mining.
Prashant Srivastava received the master’s degree in physics from the Indian Institute of Science Education and Research, Kolkata, and the master’s degree in data science and analytics from the Department of Computer Science, Royal Holloway, University of London. He is currently a Research Assistant with the Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Germany. His current research interests include algorithm development and their applications in literature mining.View more
Author image of Saptarshi Bej
Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany
Leibniz-Institute for Food Systems Biology, Technical University of Munich, Freising, Germany
Saptarshi Bej received the master’s degree in mathematics from the Indian Institute of Science Education and Research, Kolkata, in 2014. He is currently a Research Associate at the Institute of Computer Science, University of Rostock, Germany, and a Guest Scientist with the Leibniz-Institute for Food Systems Biology, Technical University of Munich, Germany. His research interests include graph theory, specifically the Barnette’s conjecture, the development of machine learning algorithms and their applications in the life sciences, machine learning on small and imbalanced datasets, and literature mining.
Saptarshi Bej received the master’s degree in mathematics from the Indian Institute of Science Education and Research, Kolkata, in 2014. He is currently a Research Associate at the Institute of Computer Science, University of Rostock, Germany, and a Guest Scientist with the Leibniz-Institute for Food Systems Biology, Technical University of Munich, Germany. His research interests include graph theory, specifically the Barnette’s conjecture, the development of machine learning algorithms and their applications in the life sciences, machine learning on small and imbalanced datasets, and literature mining.View more
Author image of Kristian Schultz
Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany
Kristian Schultz received the degrees in mathematics and computer science, in 2014. After that, he worked for two years in the field of discrete mathematics on Sperner families with the Department of Mathematics, University in Rostock, Germany. In between, he extended his software developing skills in industry. Since 2020, he returned to the Department of Systems Biology and Bioinformatics, University of Rostock, where he focuses on the correctness, efficiency, bbreak and implementation of algorithms.
Kristian Schultz received the degrees in mathematics and computer science, in 2014. After that, he worked for two years in the field of discrete mathematics on Sperner families with the Department of Mathematics, University in Rostock, Germany. In between, he extended his software developing skills in industry. Since 2020, he returned to the Department of Systems Biology and Bioinformatics, University of Rostock, where he focuses on the correctness, efficiency, bbreak and implementation of algorithms.View more
Author image of Kristina Yordanova
Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany
Kristina Yordanova received the bachelor’s degree in computer engineering from the University of Duisburg-Essen, Germany, in 2008, the master’s degree in artificial intelligence from Maastricht University, The Netherlands, in 2009, and the Ph.D. degree in ubiquitous computing from the University of Rostock, Germany, in 2014. She is currently the Head of the Junior Research Group “Cognitive Methods for Situation-Aware Assistive Systems,” University of Rostock, and a Research Associate with the University of Bristol, U.K. Her research interests include natural language processing, machine learning, and symbolic and probabilistic modeling with applications in assistive systems, social sciences, healthcare, and medicine.
Kristina Yordanova received the bachelor’s degree in computer engineering from the University of Duisburg-Essen, Germany, in 2008, the master’s degree in artificial intelligence from Maastricht University, The Netherlands, in 2009, and the Ph.D. degree in ubiquitous computing from the University of Rostock, Germany, in 2014. She is currently the Head of the Junior Research Group “Cognitive Methods for Situation-Aware Assistive Systems,” University of Rostock, and a Research Associate with the University of Bristol, U.K. Her research interests include natural language processing, machine learning, and symbolic and probabilistic modeling with applications in assistive systems, social sciences, healthcare, and medicine.View more
Author image of Olaf Wolkenhauer
Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany
Leibniz-Institute for Food Systems Biology, Technical University of Munich, Freising, Germany
Olaf Wolkenhauer received the degrees in systems and control engineering and the Ph.D. degree for research in possibility theory with applications to data analysis. He spent over ten years at the University of Manchester Institute of Science and Technology, U.K. In 2003, he was appointed as a Professor of systems biology and bioinformatics at the University of Rostock, Germany. In 2005, he became a fellow of the Stellenbosch Institute for Advanced Study and holds professorships at Case Western Reserve University, USA, and Chhattisgarh Swami Vivekanand Technical University, India. In 2015, he was elected as a member of the Foundations in Medicine and Biology Review Panel of the German Research Foundation (DFG). His research interests include data-driven modelling with model-driven experimentation, using a wide range of approaches, including machine learning and systems theory.
Olaf Wolkenhauer received the degrees in systems and control engineering and the Ph.D. degree for research in possibility theory with applications to data analysis. He spent over ten years at the University of Manchester Institute of Science and Technology, U.K. In 2003, he was appointed as a Professor of systems biology and bioinformatics at the University of Rostock, Germany. In 2005, he became a fellow of the Stellenbosch Institute for Advanced Study and holds professorships at Case Western Reserve University, USA, and Chhattisgarh Swami Vivekanand Technical University, India. In 2015, he was elected as a member of the Foundations in Medicine and Biology Review Panel of the German Research Foundation (DFG). His research interests include data-driven modelling with model-driven experimentation, using a wide range of approaches, including machine learning and systems theory.View more

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