Abstract:
This study presents a facile route to fabricate a novel kind of digital microfluidic (DMF) chip via direct ink writing. The manufacture of this device does not rely on co...Show MoreMetadata
Abstract:
This study presents a facile route to fabricate a novel kind of digital microfluidic (DMF) chip via direct ink writing. The manufacture of this device does not rely on conventional microfabrication processes and cleanrooms, which makes it easy to prepare and low cost. By measuring the change of contact angle (CA) and droplet velocity, we proved that it could perform droplet manipulation like traditional DMF chips. In addition, after optimizing the chip structure, through a peripheral support circuit, polymerase chain reaction (PCR) reagents could be automatically partitioned and mixed on the chip. Furthermore, we realized the multi-target end-point fluorescence detection of SARS-CoV-2 RNA on this chip, showing promising potential for automatic nucleic acid tests.
Published in: 2022 IEEE 35th International Conference on Micro Electro Mechanical Systems Conference (MEMS)
Date of Conference: 09-13 January 2022
Date Added to IEEE Xplore: 11 February 2022
ISBN Information: