Development Surface Morphologies of Porous Hydroxyapatite Scaffold Hydrothermally for Bone Regeneration

The development of calcium phosphate (Ca/P) surface structure is good to choose of bone substitute scaffolds, which is a favor for bone regeneration. In this study hydroxyapatite (HA) porous scaffolds were produced by the accumulation of HA fibres and treated hydrothermally in a calcium phosphate solution to form new morphology. A rodlike comprise a flower-like morphology were from on the surface of Ca-HA scaffold. The surfaces of the treated scaffold were investigated by scanning electron microscopy (SEM) and x-ray diffraction (XRD). Moreover, cell culture results showed that the endothelial cells (EC) could spread on the surfaces of the treated scaffold (Ca-HA) more than HA scaffolds (control).