I. Introduction
Callus is one of the main causes of diabetic foot ulcers. Many foot ulcers progress to lower limb amputation and can seriously affect the quality of life (QOL), reduce physical activity, and increase psychological stress [1]. In addition, even when an ulcer has successfully healed, the risk of recurrence is high, with reported rates ranging between 30% and 40% within one year [2]. Therefore, the prevention of foot ulcers is of paramount importance and has long been recognized as a priority by the International Working Group on the Diabetic Foot (IWGDF) [3].