Abstract:
Current clinical ultrasound (US) systems are limited to show blood flow movement in either 1-D or 2-D. In this paper, a method for estimating 3-D vector velocities in a p...Show MoreMetadata
Abstract:
Current clinical ultrasound (US) systems are limited to show blood flow movement in either 1-D or 2-D. In this paper, a method for estimating 3-D vector velocities in a plane using the transverse oscillation method, a 32 × 32 element matrix array, and the experimental US scanner SARUS is presented. The aim of this paper is to estimate precise flow rates and peak velocities derived from 3-D vector flow estimates. The emission sequence provides 3-D vector flow estimates at up to 1.145 frames/s in a plane, and was used to estimate 3-D vector flow in a cross-sectional image plane. The method is validated in two phantom studies, where flow rates are measured in a flow-rig, providing a constant parabolic flow, and in a straight-vessel phantom (Ø=8 mm) connected to a flow pump capable of generating time varying waveforms. Flow rates are estimated to be 82.1 ± 2.8 L/min in the flow-rig compared with the expected 79.8 L/min, and to 2.68 ± 0.04 mL/stroke in the pulsating environment compared with the expected 2.57 ± 0.08 mL/stroke. Flow rates estimated in the common carotid artery of a healthy volunteer are compared with magnetic resonance imaging (MRI) measured flow rates using a 1-D through-plane velocity sequence. Mean flow rates were 333 ± 31 mL/min for the presented method and 346 ± 2 mL/min for the MRI measurements.
Published in: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control ( Volume: 64, Issue: 3, March 2017)
Funding Agency:
Center for Fast Ultrasound Imaging, Technical University of Denmark, Lyngby, Denmark
Simon Holbek (S’14–A’16–M’16) was born in 1986. He received the M.Sc. degree in physics from the Niels Bohr Institute, Univercity of Copenhagen, Denmark, in 2013, and the Ph.D. degree from the Technical University of Denmark in 2017.
He is currently a postdoc with the Center for Fast Ultrasound Imaging at the Department of Electrical Engineering, Technical University of Denmark. His current research topic is within 3-D vec...Show More
Simon Holbek (S’14–A’16–M’16) was born in 1986. He received the M.Sc. degree in physics from the Niels Bohr Institute, Univercity of Copenhagen, Denmark, in 2013, and the Ph.D. degree from the Technical University of Denmark in 2017.
He is currently a postdoc with the Center for Fast Ultrasound Imaging at the Department of Electrical Engineering, Technical University of Denmark. His current research topic is within 3-D vec...View more
Department of Radiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Caroline Ewertsen received the Ph.D. degree in radiology from the Copenhagen University, Copenhagen, Denmark.
She is a radiologist at Copenhagen University Hospital, Rigshospitalet. She a part-time researcher at the Danish Technical University (DTU), Centre for Fast Ultrasound. She is president of the Danish Society of Diagnostic Ultrasound, Euroson congress secretary 2010, member of the EFSUMB publication committee since ...Show More
Caroline Ewertsen received the Ph.D. degree in radiology from the Copenhagen University, Copenhagen, Denmark.
She is a radiologist at Copenhagen University Hospital, Rigshospitalet. She a part-time researcher at the Danish Technical University (DTU), Centre for Fast Ultrasound. She is president of the Danish Society of Diagnostic Ultrasound, Euroson congress secretary 2010, member of the EFSUMB publication committee since ...View more
Center for Fast Ultrasound Imaging, Technical University of Denmark, Lyngby, Denmark
Hamed Bouzari (S’14–M’16) received the B.S. and M.S. degrees in electrical and electronics engineering from Mazandaran and Zanjan universities in 2006 and 2009 both from Iran. He is currently pursuing the Ph.D. degree in biomedical engineering at Technical University of Denmark.
He was a researcher at Austrian Academy of Sciences (ÖAW), Vienna, Austria, from 2010 to 2013. His research interests include all facets of high v...Show More
Hamed Bouzari (S’14–M’16) received the B.S. and M.S. degrees in electrical and electronics engineering from Mazandaran and Zanjan universities in 2006 and 2009 both from Iran. He is currently pursuing the Ph.D. degree in biomedical engineering at Technical University of Denmark.
He was a researcher at Austrian Academy of Sciences (ÖAW), Vienna, Austria, from 2010 to 2013. His research interests include all facets of high v...View more
Center for Fast Ultrasound Imaging, Technical University of Denmark, Lyngby, Denmark
Michael Johannes Pihl (S’11–M’12) was born in 1983. He received the M.Sc. degree in biomedical engineering in 2009 from the Technical University of Denmark (DTU) and the University of Copenhagen, Denmark. In 2012, he received the Ph.D. degree in biomedical engineering from the Center for Fast Ultrasound Imaging, DTU.
In 2007, he spent seven months with the Biomedical Engineering Department, Duke University, Durham, NC, USA...Show More
Michael Johannes Pihl (S’11–M’12) was born in 1983. He received the M.Sc. degree in biomedical engineering in 2009 from the Technical University of Denmark (DTU) and the University of Copenhagen, Denmark. In 2012, he received the Ph.D. degree in biomedical engineering from the Center for Fast Ultrasound Imaging, DTU.
In 2007, he spent seven months with the Biomedical Engineering Department, Duke University, Durham, NC, USA...View more
Department of Radiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Kristoffer Lindskov Hansen was born in 1974. He received the M.D. and Ph.D. degrees from Copenhagen University, Copenhagen, Denmark, in 2003 and 2010, respectively, with a focus on vector velocity and adaptive spectral estimators in medical ultrasound, and the Medical Specialist degree from Copenhagen University in radiology in 2014.
He is currently with the Department of Radiology, Rigshospitalet, Copenhagen University Ho...Show More
Kristoffer Lindskov Hansen was born in 1974. He received the M.D. and Ph.D. degrees from Copenhagen University, Copenhagen, Denmark, in 2003 and 2010, respectively, with a focus on vector velocity and adaptive spectral estimators in medical ultrasound, and the Medical Specialist degree from Copenhagen University in radiology in 2014.
He is currently with the Department of Radiology, Rigshospitalet, Copenhagen University Ho...View more
Center for Fast Ultrasound Imaging, Technical University of Denmark, Lyngby, Denmark
Matthias Bo Stuart (S’07–M’09) received the M.Sc. and Ph.D. degrees in computer engineering from the Technical University of Denmark, Lyngby, Denmark, in 2006 and 2010, respectively.
He is currently a postdoc with the Center for Fast Ultrasound Imaging, Department of Electrical Engineering, Technical University of Denmark. His research interests include synthetic aperture methods for both anatomical and flow imaging in bot...Show More
Matthias Bo Stuart (S’07–M’09) received the M.Sc. and Ph.D. degrees in computer engineering from the Technical University of Denmark, Lyngby, Denmark, in 2006 and 2010, respectively.
He is currently a postdoc with the Center for Fast Ultrasound Imaging, Department of Electrical Engineering, Technical University of Denmark. His research interests include synthetic aperture methods for both anatomical and flow imaging in bot...View more
Department of Radiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Carsten Thomsen was born in Copenhagen Denmark, in 1955. He received the M.D. degree from Copenhagen University in 1981 and the Ph.D. degree from the University of Copenhagen, Marts, in 1996, with the thesis “Quantitative magnetic resonance methods for in vivo investigation of the human liver and spleen. Technical aspects and preliminary clinical results.”
He has been the chief consultant and head of neuroradiology since 1...Show More
Carsten Thomsen was born in Copenhagen Denmark, in 1955. He received the M.D. degree from Copenhagen University in 1981 and the Ph.D. degree from the University of Copenhagen, Marts, in 1996, with the thesis “Quantitative magnetic resonance methods for in vivo investigation of the human liver and spleen. Technical aspects and preliminary clinical results.”
He has been the chief consultant and head of neuroradiology since 1...View more
Department of Radiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Michael Bachmann Nielsen is a Medical graduate from the Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark, in 1985, and received the Ph.D. degree in 1994, and the Dr. Med. Dissertation degree from Copenhagen University, Copenhagen, Denmark, in 1998.
He is a Full Professor of Oncoradiology with the University of Copenhagen, and a Consultant with the Department of Radiology, Rigshospitalet, Copenhagen....Show More
Michael Bachmann Nielsen is a Medical graduate from the Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark, in 1985, and received the Ph.D. degree in 1994, and the Dr. Med. Dissertation degree from Copenhagen University, Copenhagen, Denmark, in 1998.
He is a Full Professor of Oncoradiology with the University of Copenhagen, and a Consultant with the Department of Radiology, Rigshospitalet, Copenhagen....View more
Center for Fast Ultrasound Imaging, Technical University of Denmark, Lyngby, Denmark
Jørgen Arendt Jensen (M’93–SM’02–F’12) received the Master of Science degree in electrical engineering in 1985 and the Ph.D. degree in 1989, both from the Technical University of Denmark. He received the Dr.Techn. degree from the university in 1996.
Since 1993, he has been Full Professor of Biomedical Signal Processing with the Department of Electrical Engineering, Technical University of Denmark and head of the Center for...Show More
Jørgen Arendt Jensen (M’93–SM’02–F’12) received the Master of Science degree in electrical engineering in 1985 and the Ph.D. degree in 1989, both from the Technical University of Denmark. He received the Dr.Techn. degree from the university in 1996.
Since 1993, he has been Full Professor of Biomedical Signal Processing with the Department of Electrical Engineering, Technical University of Denmark and head of the Center for...View more
Contents Center for Fast Ultrasound Imaging, Technical University of Denmark, Lyngby, Denmark
Simon Holbek (S’14–A’16–M’16) was born in 1986. He received the M.Sc. degree in physics from the Niels Bohr Institute, Univercity of Copenhagen, Denmark, in 2013, and the Ph.D. degree from the Technical University of Denmark in 2017.
He is currently a postdoc with the Center for Fast Ultrasound Imaging at the Department of Electrical Engineering, Technical University of Denmark. His current research topic is within 3-D vector flow imaging.
Simon Holbek (S’14–A’16–M’16) was born in 1986. He received the M.Sc. degree in physics from the Niels Bohr Institute, Univercity of Copenhagen, Denmark, in 2013, and the Ph.D. degree from the Technical University of Denmark in 2017.
He is currently a postdoc with the Center for Fast Ultrasound Imaging at the Department of Electrical Engineering, Technical University of Denmark. His current research topic is within 3-D vector flow imaging.View more
Department of Radiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Caroline Ewertsen received the Ph.D. degree in radiology from the Copenhagen University, Copenhagen, Denmark.
She is a radiologist at Copenhagen University Hospital, Rigshospitalet. She a part-time researcher at the Danish Technical University (DTU), Centre for Fast Ultrasound. She is president of the Danish Society of Diagnostic Ultrasound, Euroson congress secretary 2010, member of the EFSUMB publication committee since 2013, and the organizer of several courses in ultrasound. Her research includes new ultrasound technologies such as image fusion, elastography, and novel techniques for visualizing flow. She has written more than 40 articles in peer-reviewed journals.
Caroline Ewertsen received the Ph.D. degree in radiology from the Copenhagen University, Copenhagen, Denmark.
She is a radiologist at Copenhagen University Hospital, Rigshospitalet. She a part-time researcher at the Danish Technical University (DTU), Centre for Fast Ultrasound. She is president of the Danish Society of Diagnostic Ultrasound, Euroson congress secretary 2010, member of the EFSUMB publication committee since 2013, and the organizer of several courses in ultrasound. Her research includes new ultrasound technologies such as image fusion, elastography, and novel techniques for visualizing flow. She has written more than 40 articles in peer-reviewed journals.View more
Center for Fast Ultrasound Imaging, Technical University of Denmark, Lyngby, Denmark
Hamed Bouzari (S’14–M’16) received the B.S. and M.S. degrees in electrical and electronics engineering from Mazandaran and Zanjan universities in 2006 and 2009 both from Iran. He is currently pursuing the Ph.D. degree in biomedical engineering at Technical University of Denmark.
He was a researcher at Austrian Academy of Sciences (ÖAW), Vienna, Austria, from 2010 to 2013. His research interests include all facets of high volume rate 3-D ultrasonic imaging for medical applications.
Hamed Bouzari (S’14–M’16) received the B.S. and M.S. degrees in electrical and electronics engineering from Mazandaran and Zanjan universities in 2006 and 2009 both from Iran. He is currently pursuing the Ph.D. degree in biomedical engineering at Technical University of Denmark.
He was a researcher at Austrian Academy of Sciences (ÖAW), Vienna, Austria, from 2010 to 2013. His research interests include all facets of high volume rate 3-D ultrasonic imaging for medical applications.View more
Center for Fast Ultrasound Imaging, Technical University of Denmark, Lyngby, Denmark
Michael Johannes Pihl (S’11–M’12) was born in 1983. He received the M.Sc. degree in biomedical engineering in 2009 from the Technical University of Denmark (DTU) and the University of Copenhagen, Denmark. In 2012, he received the Ph.D. degree in biomedical engineering from the Center for Fast Ultrasound Imaging, DTU.
In 2007, he spent seven months with the Biomedical Engineering Department, Duke University, Durham, NC, USA, researching ultrasonic clutter. He is currently working as algorithm developer with Widex A/S.
Michael Johannes Pihl (S’11–M’12) was born in 1983. He received the M.Sc. degree in biomedical engineering in 2009 from the Technical University of Denmark (DTU) and the University of Copenhagen, Denmark. In 2012, he received the Ph.D. degree in biomedical engineering from the Center for Fast Ultrasound Imaging, DTU.
In 2007, he spent seven months with the Biomedical Engineering Department, Duke University, Durham, NC, USA, researching ultrasonic clutter. He is currently working as algorithm developer with Widex A/S.View more
Department of Radiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Kristoffer Lindskov Hansen was born in 1974. He received the M.D. and Ph.D. degrees from Copenhagen University, Copenhagen, Denmark, in 2003 and 2010, respectively, with a focus on vector velocity and adaptive spectral estimators in medical ultrasound, and the Medical Specialist degree from Copenhagen University in radiology in 2014.
He is currently with the Department of Radiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen.
Kristoffer Lindskov Hansen was born in 1974. He received the M.D. and Ph.D. degrees from Copenhagen University, Copenhagen, Denmark, in 2003 and 2010, respectively, with a focus on vector velocity and adaptive spectral estimators in medical ultrasound, and the Medical Specialist degree from Copenhagen University in radiology in 2014.
He is currently with the Department of Radiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen.View more
Center for Fast Ultrasound Imaging, Technical University of Denmark, Lyngby, Denmark
Matthias Bo Stuart (S’07–M’09) received the M.Sc. and Ph.D. degrees in computer engineering from the Technical University of Denmark, Lyngby, Denmark, in 2006 and 2010, respectively.
He is currently a postdoc with the Center for Fast Ultrasound Imaging, Department of Electrical Engineering, Technical University of Denmark. His research interests include synthetic aperture methods for both anatomical and flow imaging in both 2-D and 3-D, ultrasound systems, and real-time implementations of ultrasound processing algorithms.
Matthias Bo Stuart (S’07–M’09) received the M.Sc. and Ph.D. degrees in computer engineering from the Technical University of Denmark, Lyngby, Denmark, in 2006 and 2010, respectively.
He is currently a postdoc with the Center for Fast Ultrasound Imaging, Department of Electrical Engineering, Technical University of Denmark. His research interests include synthetic aperture methods for both anatomical and flow imaging in both 2-D and 3-D, ultrasound systems, and real-time implementations of ultrasound processing algorithms.View more
Department of Radiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Carsten Thomsen was born in Copenhagen Denmark, in 1955. He received the M.D. degree from Copenhagen University in 1981 and the Ph.D. degree from the University of Copenhagen, Marts, in 1996, with the thesis “Quantitative magnetic resonance methods for in vivo investigation of the human liver and spleen. Technical aspects and preliminary clinical results.”
He has been the chief consultant and head of neuroradiology since 1995 and full professor in radiology at Rigshospitalet Copenhagen University since 1997. His current research activities include work on quantitative magnetic resonance imaging and spectroscopy of the brain.
Carsten Thomsen was born in Copenhagen Denmark, in 1955. He received the M.D. degree from Copenhagen University in 1981 and the Ph.D. degree from the University of Copenhagen, Marts, in 1996, with the thesis “Quantitative magnetic resonance methods for in vivo investigation of the human liver and spleen. Technical aspects and preliminary clinical results.”
He has been the chief consultant and head of neuroradiology since 1995 and full professor in radiology at Rigshospitalet Copenhagen University since 1997. His current research activities include work on quantitative magnetic resonance imaging and spectroscopy of the brain.View more
Department of Radiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Michael Bachmann Nielsen is a Medical graduate from the Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark, in 1985, and received the Ph.D. degree in 1994, and the Dr. Med. Dissertation degree from Copenhagen University, Copenhagen, Denmark, in 1998.
He is a Full Professor of Oncoradiology with the University of Copenhagen, and a Consultant with the Department of Radiology, Rigshospitalet, Copenhagen. He has authored over 200 peer-reviewed journal articles on ultrasound or radiology. His current research interests include clinical testing of new ultrasound techniques, tumor vascularity assessed with CT perfusion techniques, and training in ultrasound.
Michael Bachmann Nielsen is a Medical graduate from the Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark, in 1985, and received the Ph.D. degree in 1994, and the Dr. Med. Dissertation degree from Copenhagen University, Copenhagen, Denmark, in 1998.
He is a Full Professor of Oncoradiology with the University of Copenhagen, and a Consultant with the Department of Radiology, Rigshospitalet, Copenhagen. He has authored over 200 peer-reviewed journal articles on ultrasound or radiology. His current research interests include clinical testing of new ultrasound techniques, tumor vascularity assessed with CT perfusion techniques, and training in ultrasound.View more
Center for Fast Ultrasound Imaging, Technical University of Denmark, Lyngby, Denmark
Jørgen Arendt Jensen (M’93–SM’02–F’12) received the Master of Science degree in electrical engineering in 1985 and the Ph.D. degree in 1989, both from the Technical University of Denmark. He received the Dr.Techn. degree from the university in 1996.
Since 1993, he has been Full Professor of Biomedical Signal Processing with the Department of Electrical Engineering, Technical University of Denmark and head of the Center for Fast Ultrasound Imaging since its inauguration in 1998. He has published more than 450 journal and conference papers on signal processing and medical ultrasound and the book Estimation of Blood Velocities Using Ultrasound (Cambridge Univ. Press), 1996. He is also the developer and maintainer of the Field II simulation program. He has been a visiting scientist at Duke University, Stanford University, and the University of Illinois at Urbana-Champaign. He was head of the Biomedical Engineering group from 2007 to 2010. In 2003, he was one of the founders of the biomedical engineering program in Medicine and Technology, which is a joint degree program between the Technical University of Denmark and the Faculty of Health and Medical Sciences at the University of Copenhagen. The degree is one of the most sought-after engineering degrees in Denmark. He was chairman of the study board from 2003 to 2010 and Adjunct Professor with the University of Copenhagen from 2005 to 2010. He has given a number of short courses on simulation, synthetic aperture imaging, and flow estimation at international scientific conferences and teaches biomedical signal processing and medical imaging at the Technical University of Denmark. His research is centered around simulation of ultrasound imaging, synthetic aperture imaging, vector blood flow estimation, and construction of ultrasound research systems.
Dr. Jensen has given more than 60 invited talks at international meetings and received several awards for his research.
Jørgen Arendt Jensen (M’93–SM’02–F’12) received the Master of Science degree in electrical engineering in 1985 and the Ph.D. degree in 1989, both from the Technical University of Denmark. He received the Dr.Techn. degree from the university in 1996.
Since 1993, he has been Full Professor of Biomedical Signal Processing with the Department of Electrical Engineering, Technical University of Denmark and head of the Center for Fast Ultrasound Imaging since its inauguration in 1998. He has published more than 450 journal and conference papers on signal processing and medical ultrasound and the book Estimation of Blood Velocities Using Ultrasound (Cambridge Univ. Press), 1996. He is also the developer and maintainer of the Field II simulation program. He has been a visiting scientist at Duke University, Stanford University, and the University of Illinois at Urbana-Champaign. He was head of the Biomedical Engineering group from 2007 to 2010. In 2003, he was one of the founders of the biomedical engineering program in Medicine and Technology, which is a joint degree program between the Technical University of Denmark and the Faculty of Health and Medical Sciences at the University of Copenhagen. The degree is one of the most sought-after engineering degrees in Denmark. He was chairman of the study board from 2003 to 2010 and Adjunct Professor with the University of Copenhagen from 2005 to 2010. He has given a number of short courses on simulation, synthetic aperture imaging, and flow estimation at international scientific conferences and teaches biomedical signal processing and medical imaging at the Technical University of Denmark. His research is centered around simulation of ultrasound imaging, synthetic aperture imaging, vector blood flow estimation, and construction of ultrasound research systems.
Dr. Jensen has given more than 60 invited talks at international meetings and received several awards for his research.View more
