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Label-Free - Photonic Crystal Based Immunosensors for Diagnostic Applications | IEEE Journals & Magazine | IEEE Xplore

Label-Free \hbox{Si}_{3}\hbox{N}_{4} Photonic Crystal Based Immunosensors for Diagnostic Applications


Label-Free \hbox{Si}_{3}\hbox{N}_{4} Photonic Crystal Based Immunosensors for Diagnostic Applications.

Abstract:

Immunosensors are devices that exploit immobilized antibodies to promote the binding of specific analytes related to diseases of medical importance, such as cancer or car...Show More

Abstract:

Immunosensors are devices that exploit immobilized antibodies to promote the binding of specific analytes related to diseases of medical importance, such as cancer or cardiac dysfunctions. Label-free immunosensors have an important role, due to their simplicity and fast read-out. Here, the proof of concept for an immunosensor based on a 2-D photonic crystal silicon nitride membrane is presented. The device has been fabricated by means of a well-tuned nanofabrication protocol, achieving a high-quality photonic pattern on a large-area membrane (1 mm \times 1 mm), and it has been tested for the detection of interleukin-6, getting protein detection at pg/mL concentrations.
Label-Free \hbox{Si}_{3}\hbox{N}_{4} Photonic Crystal Based Immunosensors for Diagnostic Applications.
Published in: IEEE Photonics Journal ( Volume: 6, Issue: 6, December 2014)
Article Sequence Number: 0600507
Date of Publication: 05 September 2014

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