Abstract:
A CMOS microsystem for detecting microparticles in magnetic immunoassays uses the intrinsic dynamics of magnetization in super-paramagnetic materials to reduce measuremen...Show MoreMetadata
Abstract:
A CMOS microsystem for detecting microparticles in magnetic immunoassays uses the intrinsic dynamics of magnetization in super-paramagnetic materials to reduce measurement baseline by >;300× compared to conventional methods, and to achieve a signal to baseline ratio>; 1, with an improvement of over 50 × compared to systems that ignore bead dynamics. The microsystem integrates a 64 × 160 Hall-sensor array with column-parallel readout electronics that combine auto-zeroing and nested chopping to enable low-offset, power efficient signal acquisition and has an Allan deviation floor of 9 nT.
Published in: IEEE Journal of Solid-State Circuits ( Volume: 48, Issue: 1, January 2013)
BSAC UC Berkeley, University of California, Berkeley, CA, USA
Simone Gambini received the Laurea Specialistica degree from University of Pisa and Sant'Anna School of Advanced Studies in 2004, and the Ph.D. From U.C. Berkeley in 2009, all in electrical engineering. His doctoral research was developed at the Berkeley Wireless Research Center and was partially funded by an Intel Fellowship.
In 2010, he was with Telegent Systems, where he designed RF circuits for highly integrated mobile...Show More
Simone Gambini received the Laurea Specialistica degree from University of Pisa and Sant'Anna School of Advanced Studies in 2004, and the Ph.D. From U.C. Berkeley in 2009, all in electrical engineering. His doctoral research was developed at the Berkeley Wireless Research Center and was partially funded by an Intel Fellowship.
In 2010, he was with Telegent Systems, where he designed RF circuits for highly integrated mobile...View more
BSAC UC Berkeley, University of California, Berkeley, CA, USA
Karl Skucha is currently completing the Ph.D. In electrical engineering with a minor in management of technology at UC Berkeley, where he also received the BS and MS degrees in electrical engineering in 2006 and 2009, respectively. He is an Intel Robert Noyce Fellow and his doctoral work is focused on CMOS-integrated magnetic particle detectors for diagnostic applications.
Karl Skucha is currently completing the Ph.D. In electrical engineering with a minor in management of technology at UC Berkeley, where he also received the BS and MS degrees in electrical engineering in 2006 and 2009, respectively. He is an Intel Robert Noyce Fellow and his doctoral work is focused on CMOS-integrated magnetic particle detectors for diagnostic applications.View more
BSAC UC Berkeley, University of California, Berkeley, CA, USA
Paul Peng Liu received the B.S. degree in microelectronics from Peking University and the M.S. degree in electrical engineering from North Carolina University. He is currently pursuing the Ph.D. degree in electrical engineering at the University of California, Berkeley.
Prior to joining Berkeley in 2007, he was a staff design engineer with Xilinx Inc. working on high-speed serial link transceiver. His current research inte...Show More
Paul Peng Liu received the B.S. degree in microelectronics from Peking University and the M.S. degree in electrical engineering from North Carolina University. He is currently pursuing the Ph.D. degree in electrical engineering at the University of California, Berkeley.
Prior to joining Berkeley in 2007, he was a staff design engineer with Xilinx Inc. working on high-speed serial link transceiver. His current research inte...View more
BSAC UC Berkeley, University of California, Berkeley, CA, USA
Jungkyu Kim received the Ph.D. degree in biomedical engineering from the University of Utah, Salt Lake City, in 2009.
He is currently a Postdoctoral Researcher with the Department of Chemistry and Bioengineering, University of California, Berkeley. He has been working in the area of cell/tissue engineering, microfluidic sample processing, nucleic acid sample preparation and on-chip amplification, protein microarray, CNT bi...Show More
Jungkyu Kim received the Ph.D. degree in biomedical engineering from the University of Utah, Salt Lake City, in 2009.
He is currently a Postdoctoral Researcher with the Department of Chemistry and Bioengineering, University of California, Berkeley. He has been working in the area of cell/tissue engineering, microfluidic sample processing, nucleic acid sample preparation and on-chip amplification, protein microarray, CNT bi...View more
BSAC UC Berkeley, University of California, Berkeley, CA, USA
Reut Krigel received the Bachelor of Sciences degree in electrical engineering from Tel Aviv University, Israel, in 2011.
In the same year, she joined the University of California, Berkeley where she served as a research assistant conducting experiments on CMOS biosensors and micromachined piezo-electric ultrasound transducers.
Reut Krigel received the Bachelor of Sciences degree in electrical engineering from Tel Aviv University, Israel, in 2011.
In the same year, she joined the University of California, Berkeley where she served as a research assistant conducting experiments on CMOS biosensors and micromachined piezo-electric ultrasound transducers.View more
Contents BSAC UC Berkeley, University of California, Berkeley, CA, USA
Simone Gambini received the Laurea Specialistica degree from University of Pisa and Sant'Anna School of Advanced Studies in 2004, and the Ph.D. From U.C. Berkeley in 2009, all in electrical engineering. His doctoral research was developed at the Berkeley Wireless Research Center and was partially funded by an Intel Fellowship.
In 2010, he was with Telegent Systems, where he designed RF circuits for highly integrated mobile TV tuners. From 2011 to 2012 he was affiliated with the Berkeley Sensor and Actuator Center, where he conducted research on biosensors and MEMS interfaces. He is currently a Lecturer with the Electrical Engineering Department of the University of Melbourne (Australia). His research interests are the application of low-power electronics to create microsystems integrating sensing and communication, and the development of circuit design techniques for post-CMOS devices.
Simone Gambini received the Laurea Specialistica degree from University of Pisa and Sant'Anna School of Advanced Studies in 2004, and the Ph.D. From U.C. Berkeley in 2009, all in electrical engineering. His doctoral research was developed at the Berkeley Wireless Research Center and was partially funded by an Intel Fellowship.
In 2010, he was with Telegent Systems, where he designed RF circuits for highly integrated mobile TV tuners. From 2011 to 2012 he was affiliated with the Berkeley Sensor and Actuator Center, where he conducted research on biosensors and MEMS interfaces. He is currently a Lecturer with the Electrical Engineering Department of the University of Melbourne (Australia). His research interests are the application of low-power electronics to create microsystems integrating sensing and communication, and the development of circuit design techniques for post-CMOS devices.View more
BSAC UC Berkeley, University of California, Berkeley, CA, USA
Karl Skucha is currently completing the Ph.D. In electrical engineering with a minor in management of technology at UC Berkeley, where he also received the BS and MS degrees in electrical engineering in 2006 and 2009, respectively. He is an Intel Robert Noyce Fellow and his doctoral work is focused on CMOS-integrated magnetic particle detectors for diagnostic applications.
Karl Skucha is currently completing the Ph.D. In electrical engineering with a minor in management of technology at UC Berkeley, where he also received the BS and MS degrees in electrical engineering in 2006 and 2009, respectively. He is an Intel Robert Noyce Fellow and his doctoral work is focused on CMOS-integrated magnetic particle detectors for diagnostic applications.View more
BSAC UC Berkeley, University of California, Berkeley, CA, USA
Paul Peng Liu received the B.S. degree in microelectronics from Peking University and the M.S. degree in electrical engineering from North Carolina University. He is currently pursuing the Ph.D. degree in electrical engineering at the University of California, Berkeley.
Prior to joining Berkeley in 2007, he was a staff design engineer with Xilinx Inc. working on high-speed serial link transceiver. His current research interests include CMOS/MEMS sensor and analog/mixed-signal integrated circuit design.
Paul Peng Liu received the B.S. degree in microelectronics from Peking University and the M.S. degree in electrical engineering from North Carolina University. He is currently pursuing the Ph.D. degree in electrical engineering at the University of California, Berkeley.
Prior to joining Berkeley in 2007, he was a staff design engineer with Xilinx Inc. working on high-speed serial link transceiver. His current research interests include CMOS/MEMS sensor and analog/mixed-signal integrated circuit design.View more
BSAC UC Berkeley, University of California, Berkeley, CA, USA
Jungkyu Kim received the Ph.D. degree in biomedical engineering from the University of Utah, Salt Lake City, in 2009.
He is currently a Postdoctoral Researcher with the Department of Chemistry and Bioengineering, University of California, Berkeley. He has been working in the area of cell/tissue engineering, microfluidic sample processing, nucleic acid sample preparation and on-chip amplification, protein microarray, CNT biosensor and magnetic bead labeled immunoassay.
Dr. Kim has received numerous awards, including the Korea Research Foundation (KRF) fellowship, Pierre Lassonde Center fellowship, and the Best Paper Award from the Korea Orthopedic Research Society (KORS).
Jungkyu Kim received the Ph.D. degree in biomedical engineering from the University of Utah, Salt Lake City, in 2009.
He is currently a Postdoctoral Researcher with the Department of Chemistry and Bioengineering, University of California, Berkeley. He has been working in the area of cell/tissue engineering, microfluidic sample processing, nucleic acid sample preparation and on-chip amplification, protein microarray, CNT biosensor and magnetic bead labeled immunoassay.
Dr. Kim has received numerous awards, including the Korea Research Foundation (KRF) fellowship, Pierre Lassonde Center fellowship, and the Best Paper Award from the Korea Orthopedic Research Society (KORS).View more
BSAC UC Berkeley, University of California, Berkeley, CA, USA
Reut Krigel received the Bachelor of Sciences degree in electrical engineering from Tel Aviv University, Israel, in 2011.
In the same year, she joined the University of California, Berkeley where she served as a research assistant conducting experiments on CMOS biosensors and micromachined piezo-electric ultrasound transducers.
Reut Krigel received the Bachelor of Sciences degree in electrical engineering from Tel Aviv University, Israel, in 2011.
In the same year, she joined the University of California, Berkeley where she served as a research assistant conducting experiments on CMOS biosensors and micromachined piezo-electric ultrasound transducers.View more
