Abstract:
For wide dynamic range, compatibility with digital circuits, and low-voltage operation, the pulse modulation technique is suitable for an implanted bioimage sensor. We de...Show MoreMetadata
Abstract:
For wide dynamic range, compatibility with digital circuits, and low-voltage operation, the pulse modulation technique is suitable for an implanted bioimage sensor. We demonstrate bio-fluorescence imaging of the hippocampus in a sliced mouse brain using a pulse modulation-based image sensor. The sensor architecture and system configuration are discussed. In addition, we develop an imaging device for implantation into a mouse brain in order to measure the neural activity in the hippocampus. The device is composed of a pulse modulation image sensor with 128/spl times/128 pixels and a fiber illuminator on a polyimide substrate.
Date of Conference: 23-26 May 2005
Date Added to IEEE Xplore: 25 July 2005
Print ISBN:0-7803-8834-8
ISSN Information:
References is not available for this document.
Contents Select All
1.
P. Fromherz, "Neuroelectronic Interfacing: Semi-conductor Chips with Ion Channels, Nerve Cells, and Brain," Nanoelectronics and Information Technology, R. Waser, Ed. Wiley-VCH, Berlin, 2003, pp. 781-810.
2.
B. Eversmann, "A 128 × 128 CMOS Bio-Sensor Array for Extracellular Recording of Neural Activity," Digest of 2003 IEEE Intl Solid-State Circuits Conf. (ISSCC2003), San Francisco, CA, 2003.
3.
H. Eltoukhy, K. Salama, A. El Gamal, M. Ronaghi, and R. Davis, "A 0.18 μm CMOS 10 lux bioluminescence detection system-on-chip," Digest IEEE Intl Solid-State Circuits Conf. (ISSCC), pp. 222-223, San Francisco, CA, 2004.
4.
D. C. Ng, H. Okamoto, T. Tokuda, K. Kagawa, J. Ohta, and M. Nunoshita, "A Pulse Modulation CMOS Image Sensor with 120 dB Dynamic Range and 1 nW/cm Resolution for Bioimaging Applications," Ext. Abst. of Intl Conf. Solid State Device Materials (SSDM), pp. 384-385, Tokyo, 2004.
5.
A. Iwata, M. Nagata, N. Takeda, M. Homma, and T. Morie, "Pulse Modulation Circuit Architecture and its Application to Functional Image Sensors," Proc. IEEE International Symposium on Circuits and Systems 2000, #0113-4, pp. II-301-304, May. 2000, Geneva.
6.
V. Brajovic and T. Kanade, "A sorting image sensor and example of massively parallel intensity-to-time processing for low-latency computational sensor," IEEE Intl Conf. Robotics and Automation, pp.1638-1643, 1996.
7.
T. Lúle, B. Schneider, and M. Böhm, "Design and Fabiracation of a High-Dynamic-Range Image Sensor in TFA Technology," IEEE J. Solid-State Cir.34, pp.704-711, 1999.
8.
D. Stoppa, A. Simoni, L. Gonzo, M. Gottardi, and G.-F. D. Betta, "Novle CMOS Image Sensor With a 132-dB Dynamic Range," IEEE J. Solid-State Cir.37, pp.1846-1852, 2002.
9.
W. Yang, "A wide-dynamic-range, low power photosensor array," Digest Intl Solid-State Circuits Conf. (ISSCC), pp. 230-231, San Francisco, CA, 1994,.
10.
J. Ohta, N. Yoshida, K. Kagawa, and M. Nunoshita, "Proposal of Application of Pulsed Vision Chip for Retinal Prosthesis," Jpn. J. Appl. Phys. 41, 2322, 2002.
11.
E. Culurciello, R. Etienne-Cummings, and K. A. Boahen, "A bimorphic digital image sensor," IEEE J. Solid-State Cir., 38, pp. 281-294, 2004.
12.
K. Kagawa, K. Yasuoka, D. C. Ng, T. Furumiya, T. Tokuda, J. Ohta, M. Nunoshita, "Pulse-domain digital image processing for vision chips employing low-voltage operation in deep-submicron technologies," IEEE Selected Topics Quantum Electron., 10, pp.816-828, 2004.
13.
L. McIlrath, "A low-power low-noise ultrawide-dynamic-range CMOS imager with pixel-parallel A/D conversion," IEEE J. Solid-State Cir., 36, pp. 846-853, 2001.
14.
L. McIlrath, "A robust O(N log n) algorithm for optimal decoding of first-order SD sequences," IEEE Trans. Signal Process. 50, pp. 1942-1950, 2002.
15.
S. Kavusi and A. El Gamal, "Quantitative study of high dynamic range SD-based focal plane array architectures," Proc. SPIE, Infrared Technology and Applications XXX, 5406, 2004.
16.
K. Matsumoto-Miyai, A. Ninomiya, H. Yamasaki, H. Tamura, Y. Nakamura, and S. Shiosaka, "NMDA-Dependent Proteolysis of Presynaptic Adhesion Molecule L1 in the Hippocampus by Neuropsin," J. Neurosci 23, 7727-7736, 2003.
