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Investigating the Mechanisms of Microglia/Macrophage Activation in Mediating Inflammatory Responses Following Distraction Spinal Cord Injury | IEEE Conference Publication | IEEE Xplore

Investigating the Mechanisms of Microglia/Macrophage Activation in Mediating Inflammatory Responses Following Distraction Spinal Cord Injury


Abstract:

Background and Purpose: Scoliosis is a disease in which the 3D sequence of the spine is abnormal.[1] Distraction spinal cord injuries (DSCIs) are a common complication du...Show More

Abstract:

Background and Purpose: Scoliosis is a disease in which the 3D sequence of the spine is abnormal.[1] Distraction spinal cord injuries (DSCIs) are a common complication during severe scoliosis correction surgery, and severe cases may appear as paralysis.[2], [3] Inflammation is an important mechanism for the aggravation of DSCI, but the inflammatory pathway and microglial/macrophage activation mechanisms of DSCI are still unclear. [4]–[6] Therefore, this study aimed to investigate the role of microglia/macrophages, along with TLR4-related inflammatory pathways, in DSCIs of pig animal models.
Date of Conference: 09-09 March 2024
Date Added to IEEE Xplore: 17 September 2024
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Conference Location: Princeton, NJ, USA

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