Effect of the Three Dimensional Conformal Radiotherapy (3DCRT) Peripheral Dose on The Nipple Region of The Opposite Breast of The Obese Cancer Patients

Background: Obesity is one of the important risk factors for breast cancer and may lead to increased exposure to the opposite breast as well as alter dosage distribution during treatment. The dosage distribution on the opposite breast might be evaluated using point dose measurements. This study looked at how body mass index affected the amount of dispersed dosage that reached the opposite breast. Methods: A clinical perspective research enrolled fifty women who were diagnosed with breast cancer and handled with 3CDRT. Participants were split into two groups based on their body mass index (BMI). Three sites (P1, P2, P3) on the opposite breast were chosen for point dose assessment, one on the nipple area and the other two at the nipple area. The tests were carried out with the aid of Iba in-vivo semiconductor diode detectors. The data was analyzed using the Studentst-test. Results: Obese women had a substantially greater nipple point dosage than non-obese women ($\mathrm{P} < 0.0001$). When compared to non-obese women ($\mathrm{r}=0.261,\mathrm{P}=0.207$), BMI linked strongly and directly with the dosage that reached the site (P2) of the opposite breast in which the radiation was laterally applied in obese women ($\mathrm{r}=0.409,\mathrm{P}=0.042$). Conclusions: When the radiotherapy was laterally focused, BMI had a substantial influence on the total nipple point dosage as well as a significant and positive correlation with the dose that entered the point P2 of the obese women.