Impact Statement:Take-Home Messages •An innovative multi-frequency hyperthermia treatment planning strategy addressing the limiting clinical need represented by minimizing undesired heati...Show More
Abstract:
In hyperthermia treatments, the possibility of generating a specific absorption rate distribution peaked into the tumor and bounded elsewhere represents the main clinical...Show MoreMetadata
Impact Statement:
Take-Home Messages •An innovative multi-frequency hyperthermia treatment planning strategy addressing the limiting clinical need represented by minimizing undesired heating is presented. •This multi-frequency planning strategy, mf-FOCO, based on a convex programming problem, ensure a safe and efficient outcome of the treatment. •The targeted medical application is hyperthermia treatment planning. •Preliminary results confirmed the possibility of counteracting undesired heating exploiting multifrequency applicator while enforcing a patient-specific mask.
Abstract:
In hyperthermia treatments, the possibility of generating a specific absorption rate distribution peaked into the tumor and bounded elsewhere represents the main clinical need. As multi-frequency applicators can be exploited to reduce the occurrence of undesired hot-spots, an optimal multi-frequency approach is proposed and discussed. Being formulated in terms of a convex programming problem, the globally optimal solution can be determined (only for very special cases). The procedure, presented for the case of scalar fields, can be extended both to the case of vector fields and to the more interesting problem of shaping (rather than just focusing) the specific absorption rate distribution.
Published in: IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology ( Volume: 1, Issue: 2, December 2017)