Steric effects at acyclic and bridgehead carbons attached to carbonyls | IEEE Conference Publication | IEEE Xplore

Steric effects at acyclic and bridgehead carbons attached to carbonyls


Abstract:

The rates of alkaline hydrolysis of seven acyclic and bridgehead esters of p-nitrophenyl carboxylic acids have been kinetically found to vary inversely with the size of t...Show More

Abstract:

The rates of alkaline hydrolysis of seven acyclic and bridgehead esters of p-nitrophenyl carboxylic acids have been kinetically found to vary inversely with the size of the substituent R group. Computer assisted molecular modeling techniques were used to suggest a steric and electrostatic rationale for the effect of R group size upon the rate of hydrolysis.
Date of Conference: 29 October 1992 - 01 November 1992
Date Added to IEEE Xplore: 02 May 2011
ISBN Information:
Conference Location: Paris, France

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