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Combination of gene expression and genome copy number alteration has a prognostic value for breast cancer | IEEE Conference Publication | IEEE Xplore

Combination of gene expression and genome copy number alteration has a prognostic value for breast cancer


Abstract:

Specific genome copy number alterations, such as deletions and amplifications are an important factor in tumor development and progression, and are also associated with c...Show More

Abstract:

Specific genome copy number alterations, such as deletions and amplifications are an important factor in tumor development and progression, and are also associated with changes in gene expression. By combining analyses of gene expression and genome copy number we identified genes as candidate biomarkers of BC which were validated as prognostic factors of the disease progression. These results suggest that the proposed combined approach may become a valuable method for BC prognosis.
Date of Conference: 03-07 July 2013
Date Added to IEEE Xplore: 26 September 2013
Electronic ISBN:978-1-4577-0216-7

ISSN Information:

PubMed ID: 24109760
Conference Location: Osaka, Japan

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