# IEEE Transactions on Biomedical Engineering

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Displaying Results 1 - 25 of 40

Publication Year: 2006, Page(s):c1 - c4
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• ### IEEE Transactions on Biomedical Engineering publication information

Publication Year: 2006, Page(s): c2
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• ### Building maps of local apparent conductivity of the epicardium with a 2-D electrophysiological model of the heart

Publication Year: 2006, Page(s):1457 - 1466
Cited by:  Papers (15)
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In this paper, we address the problem of estimating the parameters of an electrophysiological model of the heart from a set of electrical recordings. The chosen model is the reaction-diffusion model on the transmembrane potential proposed by Aliev and Panfilov. For this model of the transmembrane, we estimate a local apparent two-dimensional conductivity from a measured depolarization time distrib... View full abstract»

• ### A spatiotemporal, patient individualized simulation model of solid tumor response to chemotherapy in vivo: the paradigm of glioblastoma multiforme treated by temozolomide

Publication Year: 2006, Page(s):1467 - 1477
Cited by:  Papers (32)
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A novel four-dimensional, patient-specific Monte Carlo simulation model of solid tumor response to chemotherapeutic treatment in vivo is presented. The special case of glioblastoma multiforme treated by temozolomide is addressed as a simulation paradigm. Nevertheless, a considerable number of the involved algorithms are generally applicable. The model is based on the patient's imaging, histopathol... View full abstract»

• ### Model-based blood glucose control for type 1 diabetes via parametric programming

Publication Year: 2006, Page(s):1478 - 1491
Cited by:  Papers (116)  |  Patents (1)
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An advanced model-based control technique for regulating the blood glucose for patients with Type 1 diabetes is presented. The optimal insulin delivery rate is obtained off-line as an explicit function of the current blood glucose concentration of the patient by using novel parametric programming algorithms, developed at Imperial College London. The implementation of the optimal insulin delivery r... View full abstract»

• ### Experimental verification of theoretical predictions concerning the optimum defibrillation waveform

Publication Year: 2006, Page(s):1492 - 1498
Cited by:  Papers (6)  |  Patents (5)
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The efficacy of electrical therapy at terminating ventricular fibrillation is highly dependent on the waveform used. We present experimental results which test one theory for defibrillation waveform dependence. Forty-four defibrillation waveforms (22 monophasic, 22 biphasic) were designed according to the theoretical construct of Fishler (2000). The waveforms were then tested on 67 male guinea pig... View full abstract»

• ### The Role of the Hyperpolarization-Activated Inward Current<tex>$I_rm f$</tex>in Arrhythmogenesis: A Computer Model Study

Publication Year: 2006, Page(s):1499 - 1511
Cited by:  Papers (10)
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Atrial fibrillation is the most common cardiac arrhythmia. Structural cardiac defects such as fibrosis and gap junction remodeling lead to a reduced cellular electrical coupling and are known to promote atrial fibrillation. It has been observed that the expression of the hyperpolarization-activated current I<sub>f</sub> is increased under pathological conditions. Recent experimental da... View full abstract»

• ### Computer modeling of ventricular rhythm during atrial fibrillation and ventricular pacing

Publication Year: 2006, Page(s):1512 - 1520
Cited by:  Papers (24)  |  Patents (1)
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We propose a unified atrial fibrillation (AF)-ventricular pacing (VP) (AF-VP) model to demonstrate the effects of VP on the ventricular rhythm during atrial fibrillation AF. In this model, the AV junction (AVJ) is treated as a lumped structure characterized by refractoriness and automaticity. Bombarded by random AF impulses, the AVJ can also be invaded by the VP-induced retrograde wave. The model ... View full abstract»

• ### A weighted-principal component regression method for the identification of physiologic systems

Publication Year: 2006, Page(s):1521 - 1530
Cited by:  Papers (7)
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We introduce a system identification method based on weighted-principal component regression (WPCR). This approach aims to identify the dynamics in a linear time-invariant (LTI) model which may represent a resting physiologic system. It tackles the time-domain system identification problem by considering, asymptotically, frequency information inherent in the given data. By including in the model o... View full abstract»

• ### An association rule mining-based methodology for automated detection of ischemic ECG beats

Publication Year: 2006, Page(s):1531 - 1540
Cited by:  Papers (42)  |  Patents (2)
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Currently, an automated methodology based on association rules is presented for the detection of ischemic beats in long duration electrocardiographic (ECG) recordings. The proposed approach consists of three stages. 1) Preprocessing: Noise is removed and all the necessary ECG features are extracted. 2) Discretization: The continuous valued features are transformed to categorical. 3) Classification... View full abstract»

• ### ECG signal analysis through hidden Markov models

Publication Year: 2006, Page(s):1541 - 1549
Cited by:  Papers (111)  |  Patents (5)
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This paper presents an original hidden Markov model (HMM) approach for online beat segmentation and classification of electrocardiograms. The HMM framework has been visited because of its ability of beat detection, segmentation and classification, highly suitable to the electrocardiogram (ECG) problem. Our approach addresses a large panel of topics some of them never studied before in other HMM re... View full abstract»

• ### Quantitative indices for the assessment of the repeatability of distortion product otoacoustic emissions in laboratory animals

Publication Year: 2006, Page(s):1550 - 1556
Cited by:  Papers (4)
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Distortion product otoacoustic emissions (DPOAE) can be used to study cochlear function in an objective and non-invasive manner. One practical and essential aspect of any investigating measure is the consistency of its results upon repeated testing of the same individual/animal (i.e., its test/retest repeatability). The goal of the present work is to propose two indices to quantitatively assess th... View full abstract»

• ### Development and assessment of methods for detecting dementia using the human electroencephalogram

Publication Year: 2006, Page(s):1557 - 1568
Cited by:  Papers (57)
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This paper makes an outline case for the need for a low-cost, easy to administer method for detecting dementia within the growing at risk population. It proposes two methods for electroencephalogram (EEG) analysis for detecting dementia that could fulfil such a need. The paper describes a fractal dimension-based method for analyzing the EEG waveforms of subjects with dementia and reports on an ass... View full abstract»

• ### Tracking tremor frequency in spike trains using the extended Kalman smoother

Publication Year: 2006, Page(s):1569 - 1577
Cited by:  Papers (17)
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Tremor is one of the most disabling symptoms in patients with many movement disorders including Parkinson's disease (PD) and essential tremor (ET). Neural tremor manifests itself as a quasi-periodic fluctuation of the firing rate. We describe a frequency tracking method based on the extended Kalman smoother (EKS) to estimate the instantaneous tremor frequency (ITF) exhibited in binary spike trains... View full abstract»

• ### Evaluating sleepiness using force platform posturography

Publication Year: 2006, Page(s):1578 - 1585
Cited by:  Papers (17)
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We have investigated the feasibility to use posturography as a method to estimate sleep deprivation. This manuscript presents a proof-of-concept of this idea. Twenty-one healthy subjects aged 20-37 years participated in the study. The subjects were deprived of sleep for up to 36 h. Their postural stability was measured as a function of sleep deprivation time. As a reference the critical fusion fre... View full abstract»

• ### Multiscale Detection of Transient Evoked Otoacoustic Emissions

Publication Year: 2006, Page(s):1586 - 1593
Cited by:  Papers (9)
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This paper presents a unified approach to multiscale detection of transient evoked otoacoustic emissions (TEOAEs). Using statistical detection theory, it is shown that the optimal detector involves a time windowing operation where the window can be estimated from ensemble correlation information. The detector performs adaptive splitting of the signal into different frequency bands using either wav... View full abstract»

• ### Reconstruction Quality and Spectral Content of an Electromagnetic Time-Domain Inversion Algorithm

Publication Year: 2006, Page(s):1594 - 1604
Cited by:  Papers (80)  |  Patents (1)
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A tomographic time-domain reconstruction algorithm for solving the inverse electromagnetic problem is described. The application we have in mind is dielectric breast cancer detection but the results are of general interest to the field of microwave tomography. Reconstructions have been made from experimental and numerically simulated data for objects of different sizes in order to investigate the ... View full abstract»

• ### Modeling of Muscle Motor Unit Innervation Process Correlation and Common Drive

Publication Year: 2006, Page(s):1605 - 1614
Cited by:  Papers (4)
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Concurrently active motor units (MUs) of a given muscle can exhibit a certain degree of synchronous firings, and a certain degree of common variation in their firing rates. The former property is referred to as motor unit synchrony in the literature, which is termed motor unit innervation process (MUIP) correlation in this study. The latter is referred to as motor unit common drive and can be quan... View full abstract»

• ### Automated 2-D Cephalometric Analysis on X-ray Images by a Model-Based Approach

Publication Year: 2006, Page(s):1615 - 1623
Cited by:  Papers (20)  |  Patents (8)
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Craniofacial landmark localization and anatomical structure tracing on cephalograms are two important ways to obtain the cephalometric analysis. In order to computerize them in parallel, a model-based approach is proposed to locate 262 craniofacial feature points, including 90 landmarks and 172 auxiliary points. In model training, 12 landmarks are selected as reference points and used to divide ev... View full abstract»

• ### Subspace Projection Filters for Real-Time Brain Electromagnetic Imaging

Publication Year: 2006, Page(s):1624 - 1634
Cited by:  Papers (42)
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An increasing number of neuroimaging laboratories are becoming interested in real-time investigations of the human brain. The opportunities offered by real-time applications are inversely proportional to the latency of the brain activity response and to the computational delay of brain activity estimation. Electromagnetic tomographies, based on electroencephalography (EEG) or magnetoencephalograph... View full abstract»

• ### An Improved Electronic Colon Cleansing Method for Detection of Colonic Polyps by Virtual Colonoscopy

Publication Year: 2006, Page(s):1635 - 1646
Cited by:  Papers (39)  |  Patents (4)
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Electronic colon cleansing (ECC) aims to segment the colon lumen from a patient abdominal image acquired using an oral contrast agent for colonic material tagging, so that a virtual colon model can be constructed. Virtual colonoscopy (VC) provides fly-through navigation within the colon model, looking for polyps on the inner surface in a manner analogous to that of fiber optic colonoscopy. We have... View full abstract»

• ### Multistatic Adaptive Microwave Imaging for Early Breast Cancer Detection

Publication Year: 2006, Page(s):1647 - 1657
Cited by:  Papers (124)  |  Patents (2)
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We propose a new multistatic adaptive microwave imaging (MAMI) method for early breast cancer detection. MAMI is a two-stage robust Capon beamforming (RCB) based image formation algorithm. MAMI exhibits higher resolution, lower sidelobes, and better noise and interference rejection capabilities than the existing approaches. The effectiveness of using MAMI for breast cancer detection is demonstrate... View full abstract»

• ### Correlation Between Peak Spatial-Average SAR and Temperature Increase Due to Antennas Attached to Human Trunk

Publication Year: 2006, Page(s):1658 - 1664
Cited by:  Papers (28)
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This paper discusses the correlation between peak spatial-average specific absorption rate (SAR) and maximum temperature increase for antennas attached to the human trunk. Frequency bands considered are 150, 400, and 900 MHz, which are assigned for occupational communications. This problem is thoroughly investigated with the aid of Green's function. In particular, the effect of variation of therma... View full abstract»

• ### Ultrasonically Actuated Silicon Microprobes for Cardiac Signal Recording

Publication Year: 2006, Page(s):1665 - 1671
Cited by:  Papers (13)  |  Patents (1)
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In this paper, we report on ultrasonically actuated silicon thin microprobes that successfully penetrated canine cardiac tissue in vitro, and recorded the electrophysiological signals from multiple sites simultaneously within the heart wall. The penetration force-maximum force encountered by the probe during penetration-is found to reduce with increasing ultrasonic driving voltage, on both excised... View full abstract»

• ### A Novel High Channel-Count System for Acute Multisite Neuronal Recordings

Publication Year: 2006, Page(s):1672 - 1677
Cited by:  Papers (8)
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Multisite recording represents a suitable condition to study microphysiology and network interactions in the central nervous system and, therefore, to understand brain functions. Several different materials and array configurations have been proposed for the development of new probes utilized to record brain activity from experimental animal models. We describe new multisite silicon probes that br... View full abstract»

## Aims & Scope

IEEE Transactions on Biomedical Engineering contains basic and applied papers dealing with biomedical engineering. Papers range from engineering development in methods and techniques with biomedical applications to experimental and clinical investigations with engineering contributions.

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## Meet Our Editors

Editor-in-Chief
Bin He
Carnegie Mellon University