Issue 4 • Dec. 2017

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  • Table of contents

    Publication Year: 2017, Page(s): C1
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  • The Age-Related Effect of Nicotine on the Expression of Neuroprotective Genes in Ventral Tegmental Area and Substantia Nigra

    Publication Year: 2017, Page(s):13 - 16
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (2970 KB) | HTML iconHTML

    Selective degeneration of dopaminergic neurons, which are predominantly located in the substantia nigra (SN) of the midbrain, is one of the hallmarks of Parkinson's disease (PD). Large-scale microarray experimental data revealed several genes with significantly differential expression between the ventral tegmental area (VTA) and the SN dopamine (DA) neurons. Several epidemiological studies have ad... View full abstract»

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The IEEE Life Sciences Letters (LSL) is dedicated to the timely publication of high quality manuscripts that apply methods of quantitative analysis to biological problems at the molecular, cellular, organ, human and/or population levels. The key scientific themes addressed by the journal include personalized medicine, pharmaceutical engineering, synthetic biology, and systems biology.

This Letters ceased publication in 2017.

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Paolo Bonato

Harvard Medical School

Boston, MA, USA

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