2009 First Annual ORNL Biomedical Science & Engineering Conference

18-19 March 2009

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  • [Front cover]

    Publication Year: 2009, Page(s): c1
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  • General co-chairs' welcome

    Publication Year: 2009, Page(s):1 - 2
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  • [Copyright notice]

    Publication Year: 2009, Page(s): 1
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  • Program Committee

    Publication Year: 2009, Page(s): 1
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  • Program

    Publication Year: 2009, Page(s):1 - 7
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  • “Keeping up with Bioinformatics and Computational Biology as applied to biomedicine—Where has it been? Where is it going?”

    Publication Year: 2009, Page(s):1 - 2
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  • “Imaging in the age of medical bioinformatics”

    Publication Year: 2009, Page(s): 1
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  • Learning cue phrase patterns from radiology reports using a genetic algorithm

    Publication Year: 2009, Page(s):1 - 4
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (345 KB) | HTML iconHTML

    Various computer-assisted technologies have been developed to assist radiologists in detecting cancer; however, the algorithms still lack high degrees of sensitivity and specificity, and must undergo machine learning against a training set with known pathologies in order to further refine the algorithms with higher validity of truth. This work describes an approach to learning cue phrase patterns ... View full abstract»

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  • “Dosimetric optimization of interstitial gene therapy delivery systems”

    Publication Year: 2009, Page(s):1 - 2
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  • “Biomedical innovation lessons learned during the MCAMS discovery process”

    Publication Year: 2009, Page(s):1 - 2
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  • “MRI brain extraction using a graph cut based active contour model”

    Publication Year: 2009, Page(s):1 - 2
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  • “Decoding neural activity from an intracortical implant in humans with tetraplegia”

    Publication Year: 2009, Page(s): 1
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  • “Defense Health Information System as a case study for national health IT”

    Publication Year: 2009, Page(s):1 - 2
    Cited by:  Papers (1)
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  • “Blast-related traumatic brain injury research gaps”

    Publication Year: 2009, Page(s):1 - 2
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  • “Status of the medical modernization program in the Air Force Air Combat Command”

    Publication Year: 2009, Page(s): 1
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  • “The Physiome: Genes to organism, modeling toward human health”

    Publication Year: 2009, Page(s):1 - 2
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  • Systems biology and multi-scale modeling of the heart

    Publication Year: 2009, Page(s):1 - 3
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1335 KB) | HTML iconHTML

    We are developing functionally integrated cell systems models of cardiac metabolism, signal transduction, excitation-contraction coupling, and myofilament interactions. These are then being incorporated into structurally integrated multi-scale models of cardiac electromechanical interactions that include tissue, organ and system scale properties. We describe new results with these models in which ... View full abstract»

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  • Computational modeling in quantitative cancer imaging

    Publication Year: 2009, Page(s):1 - 4
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (55 KB) | HTML iconHTML

    In recent years there have been dramatic increases in the range and quality of information available from non-invasive imaging methods so that a number of potentially valuable metrics are now available to quantitatively assess tumor status. Several of these have been used in both pre-clinical studies of animal models and clinical trials involving patients. However, the optimal methods by which the... View full abstract»

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  • “Combined experimental and modeling approach to cell motility and its role in tumor growth dynamics”

    Publication Year: 2009, Page(s):1 - 2
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  • Role of the microenvironment and feedback signaling loops in stabilizing disease states

    Publication Year: 2009, Page(s):1 - 4
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (304 KB) | HTML iconHTML

    In this paper, we identify several of the feedback loops that we posit play key roles in establishing and maintaining states of disease in the human body. These routes are established through signaling between the affected cells and cells in their local microenvironment. Signals sent and received by these cells underlie the pathogenesis of diseases ranging from type 2 diabetes and atherosclerosis ... View full abstract»

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  • “Discrete event models in biology: Problems, solutions, and food for thought”

    Publication Year: 2009, Page(s): 1
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  • A review of diagnosis methods for heart rhythm disorders

    Publication Year: 2009, Page(s):1 - 4
    Cited by:  Papers (1)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (201 KB) | HTML iconHTML

    The human cardiovascular system exhibits complicated dynamics. Various signal analysis techniques have been utilized to study electrocardiogram (ECG) rate and morphology for their potentials in diagnosis and prediction of cardiovascular diseases. Conventional methods of linear signal theory, including power spectral analysis and time-domain analysis, have been widely adopted to analyze heart rhyth... View full abstract»

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  • “Optimal Control applied to a CPR model with chest and abdominal pressures”

    Publication Year: 2009, Page(s): 1
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  • “Translating novel engineering concepts into biomedical research programs and clinical medicine”

    Publication Year: 2009, Page(s):1 - 2
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  • “Development of computational methods for neurobiological research“

    Publication Year: 2009, Page(s): 1
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