MEMS, NANO and Smart Systems, 2004. ICMENS 2004. Proceedings. 2004 International Conference on

25-27 Aug. 2004

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  • 2004 International Conference on MEMS, NANO and Smart Systems - Cover

    Publication Year: 2004, Page(s): c1
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  • 2004 International Conference on MEMS, NANO and Smart Systems - Title Page

    Publication Year: 2004, Page(s):i - iii
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  • 2004 International Conference on MEMS, NANO and Smart Systems - Copyright Page

    Publication Year: 2004, Page(s): iv
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  • 2004 International Conference on MEMS, NANO and Smart Systems - Table of contents

    Publication Year: 2004, Page(s):v - xvi
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  • Preface

    Publication Year: 2004, Page(s):xvii - xviii
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  • Organizing Committee

    Publication Year: 2004, Page(s):xix - xxiv
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  • Integrative Technology Engineering Emergent Behavior into Materials and Systems

    Publication Year: 2004, Page(s): 2
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  • Smart Polymeric Micelles as Nanocarriers for Gene and Drug Delivery

    Publication Year: 2004, Page(s):4 - 5
    Cited by:  Papers (1)
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (57 KB) | HTML iconHTML

    Block copolymers with amphiphilic character, having a large solubility difference between hydrophilic and hydrophobic segments, are known to assemble in an aqueous milieu into polymeric micelles with a mesoscopic size range. These micelles have a fairly narrow size distribution and are featured by their unique core-shell architecture, where hydrophobic segments are segregated from the aqueous exte... View full abstract»

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  • Supramolecular Design of Polyrotaxanes as Advanced Nano-Biomaterials

    Publication Year: 2004, Page(s):6 - 7
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (84 KB) | HTML iconHTML

    Supramolecular architectures have been extensively studied in the last decade [1]. In particular, polyrotaxanes have been much interested as a novel class of molecular assemblies, in which cyclic compounds are threaded onto a linear polymeric chain capped with bulky end-groups. We have systematically studied a variety of biodegradable polyrotaxanes consisting of many cyclodextrins such as α-cyclod... View full abstract»

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  • Self-Assembled Organic Nanotubes: A Novel Platform for Drug Design and Discovery

    Publication Year: 2004, Page(s): 8
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (37 KB) | HTML iconHTML

    Self-assembly and self-organization processes are the thread that connects the reductionism of chemical reactions to the complexity and emergence of a living dynamic system. Artificial self-assembly derives its principles from nature and its processes, and uses this understanding to design nanoscale devices with predefined function. However, complex forms of organized matter cannot be synthesized ... View full abstract»

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  • Nano-Engineered Polymeric Micelles for Drug Delivery to Resistant Tumor

    Publication Year: 2004, Page(s): 9
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    Amphiphilic macromolecules self-assemble to nanoscopic core/shell structures in an aqueous environment, namely polymeric micelles that can encapsulate water insoluble drugs, proteins and DNA, and target therapeutics to their site of action in a passive or active way. Polymeric micelles share many structural and functional features with natural transport system, e.g., virus and lipoproteins. The ve... View full abstract»

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  • Fast Prototyping of Protein Reaction Microfluidic Chips

    Publication Year: 2004, Page(s):12 - 16
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (258 KB) | HTML iconHTML

    This paper presents an innovative approach for the prototyping of a microfluidic chip. By design modularization, unit mold batch fabrication, and mold assembly, the prototyping of polymeric microfluidic chips can be efficient and cost effective. The development of a microfluidic chip for protein reactions, including structure fabrication and chip testing for the initial and modified versions, is r... View full abstract»

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  • A Numerical Investigation of an Electrostatic-Peristaltic Colloidal Micro Pump

    Publication Year: 2004, Page(s):17 - 21
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (308 KB) | HTML iconHTML

    An electrostatically driven peristaltic micropump is presented in this paper. A colloidal particle suspended in an electrolyte inside a charged cylindrical capillary will experience an electrical double layer force due to the charged capillary wall. Perturbations in the geometry of the capillary wall result in modification of the electrical force on the particle. If moving these perturbations of t... View full abstract»

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  • Structure and Stability of Self-Assembled Monolayers for Octadecanethiol Adsorbed onto Flame-Annealed Gold Substrate and Its Potential Application to Microfluidics

    Publication Year: 2004, Page(s):22 - 25
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (214 KB) | HTML iconHTML

    Self-Assembled Monolayers (SAMs) derived from the adsorption of organothiols onto gold have been extensively investigated for studying their potential applications to Micro- and Nanofluidics system. However, nearly all applications rely on SAMs' stability. Because high energy gold is easy to absorb organic contaminant from ambient, totally wetting gold surface can not be obtained in the laboratory... View full abstract»

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  • Fabrications of Micro-Channel Device by Hot Emboss and Direct Bonding of PMMA

    Publication Year: 2004, Page(s):26 - 29
    Cited by:  Papers (3)
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (1706 KB) | HTML iconHTML

    We have fabricated and evaluated the mechanical, optical and fluidic characteristics a 50µm wide and a 30µm deep micro-channel device produced by hot emboss and direct bonding of PMMA plate with dimensions of 20mm × 20mm × 1mm. The fabricated micro-channel device was evaluated the bond strength, which was confirmed to be high enough for practical use as well as ... View full abstract»

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  • Conformations of Super-Elastic Carbon Micro/Nano-Springs and Their Properties

    Publication Year: 2004, Page(s):32 - 35
    Cited by:  Papers (1)
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (468 KB) | HTML iconHTML

    Double-helix carbon micro-springs were prepared by the Ni catalyzed pyrolysis of acetylene containing a small amount of H2S, in high purity (almost 100% among the deposits) and yield (about 20% versus acetylene feed). The conformation and some properties of the carbon micro-springs were examined, and the potential applications were discussed. It was found that they have super-elastic properties, a... View full abstract»

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  • A Platinum Nanowires Actuator: Metallic Nano-Muscles

    Publication Year: 2004, Page(s):36 - 40
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    In this paper, we report the fabrication and characterization of electro-chemical actuator using platinum nanowire networks. Reversible strain amplitudes of ~ 0.04% have been observed by controlling the surface electronic charge density of the nanowire network through an applied voltage in an electrolyte solution. Displacement amplitudes of up to 3mm was observed for an applied voltage of only &am... View full abstract»

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  • Surface Oriented Self Assembled Growth of Carbon Nanotubes

    Publication Year: 2004, Page(s):41 - 47
    Cited by:  Papers (1)
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (1231 KB) | HTML iconHTML

    We report the self assembled surface oriented growth of single walled carbon nanotubes along the surface of (100), (110) and (111) silicon wafers using thermal CVD. The nanotubes were grown using iron nanoparticles, 10 nm in diameter, as the catalyst. The growth was carried out at 1000oC in a methane atmosphere. The lattice matching of the silicon and iron crystal lattices led to the formation of ... View full abstract»

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  • Functionalization of Carbon Nanotubes with Antibodies for Breast Cancer Detection Applications

    Publication Year: 2004, Page(s):48 - 53
    Cited by:  Papers (1)  |  Patents (1)
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (899 KB) | HTML iconHTML

    We study the effect of functionalization of Carbon Nanotubes (CNTs) with a primary monoclonal mouse immunoglobin G (IgG) specific to the cell-surface receptors of breast cancer cells, and secondary polyclonal goat ant- mouse IgG. The CNTs, in solution with a surfactant (sodium dodecyl benzene sulfonate) were labeled with dihexyloxacarbocyanine iodide (DiOC6), a fluorescent dye, in order to view th... View full abstract»

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  • Delivery of Hydrophobic Drugs through Self-Assembling Nanostructures

    Publication Year: 2004, Page(s):56 - 57
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    Many potent therapeutic agents possess a high degree of hydrophobicity which can greatly impede their solubilization in aqueous media and thus hamper their oral or parenteral administration. In order to circumvent this limitation, novel drug delivery systems, such as polymeric micelles and lipid-based nanocapsules, are being developed. In general, these nano-sized carriers contain a hydrophobic co... View full abstract»

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  • ABC Micelles for Drug Delivery - Nanoscopic Vehicles for Potent Yet Toxic and Poorly Water-Soluble Compounds

    Publication Year: 2004, Page(s): 58
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    Amphiphilic block copolymers (ABCs) assemble into nanoscopic supramolecular core-shell structures called micelles, which are under extensive study for drug delivery. The shell of ABC micelles consists of poly(ethylene glycol) (PEG), a non-toxic water-soluble polymer, which prevents protein adsorption and cellular adhesion, and the core of ABC micelles consists of a smaller hydrophobic block or par... View full abstract»

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  • New Biocompatible Nanoparticles Based on Fractionized Gelatin as Drug Delivery Systems for Nucleic Acids and Peptides

    Publication Year: 2004, Page(s): 59
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (48 KB)

    In 1978 Marty et al. described for the first time the preparation of gelatin nanoparticles using desalting or desolvating agents. The desolvation process using acetone or other non-solvents works only with very low concentrations of gelatin (0.1%) [1]. By increasing the gelatin concentration in the solution the formation of aggregations during desolvation and cosslinking also dramatically increase... View full abstract»

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  • In Vitro Gene Transfection with Surface-Modified Gelatin Nanoparticles

    Publication Year: 2004, Page(s):60 - 63
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    With the development of the two step desolvation method for the preparation of gelatin nanoparticles, it is possible to reproducibly generate homogeneous colloidal spheres. After the establishment of a surface modification to achieve stable nucleotide loading onto the particles, the goal of this study was to test this new biodegradable and simple producible non-viral gene delivery system in vitro.... View full abstract»

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  • Electrowetting on Dielectric: A Low Voltage Study on Self-Assembled Monolayers and Its Wetting Kinetics

    Publication Year: 2004, Page(s):66 - 71
    Cited by:  Papers (1)
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (276 KB) | HTML iconHTML

    A systematic study of electrowetting using alkanethiolate self-assembled monolayers (SAMs) as a dielectric layer is presented. SAMs surfaces are characterized by means of ellipsometry, and contact angle measurement. It is demonstrated that droplet spreading can be induced by a much lower voltage (4 volts), although SAMs appear to be irreversible at this operating potential. Experimental results sh... View full abstract»

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  • A Compact Chemical-Resistant Microvalve Array Using Parylene Membrane and Pneumatic Actuation

    Publication Year: 2004, Page(s):72 - 76
    Cited by:  Papers (2)  |  Patents (1)
    Request permission for reuse | Click to expandAbstract | PDF file iconPDF (215 KB) | HTML iconHTML

    A pneumatic microvalve array was designed and fabricated using silicon/glass bulk micromachining and a new parylene bonding technique. The valve membrane is made of parylene, thus has very compact size (300 µm x 300 µm) and excellent chemical resistance. The operation of valves was characterized to reveal the effects of several parameters such as actuation and inlet pressure. The valve demonstrate... View full abstract»

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