Prostate tumour growth modelled by a statistically-modulated PUN scheme

Prostate tumor (PT) normally has an indolent course during the first 10 to 15 years. Tumor progression and its clinical management, in the elderly patients, is therefore becoming a social problem, and the feasibility of non-therapeutic approaches, such as the Wait & Watch (W&W) one, requires a better understanding of the tumor natural history. Our model aims at connecting physical, biological and statistical knowledge in order to validate empirical views and to propose to clinicians a simple and effective `therapy-simulator', based on a large experimental sample, helping them in the difficult goal of personalizing patients' therapy.