Scheduled System Maintenance on May 29th, 2015:
IEEE Xplore will be upgraded between 11:00 AM and 10:00 PM EDT. During this time there may be intermittent impact on performance. We apologize for any inconvenience.
By Topic

VBM analysis of white matter volume in children with ametropic amblyopia

Sign In

Full text access may be available.

To access full text, please use your member or institutional sign in.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

6 Author(s)
Qinying Jiang ; Inst. of Med. Imaging, Tianjin Med. Univ., Tianjin, China ; Qian Li ; Mingxia Guo ; Wei Han
more authors

A number of researches have studied the neurophysiological bases of amblyopia, and most of these studies focused on the gray matter alterations. For the purpose of elucidating whether there would be any changes in the white matter, a combination of high-resolution anatomic MRI and vision tests were used to compare a group of children with ametropic amblyopia and control subjects. An automated and unbiased method called voxel-based morphometry (VBM) was employed to analyze the anatomical brain images. After performing two sample t-tests, decreased white matter volume were detected in ametropic amblyopic children versus controls. The involved regions were predominantly in the occipital lobes bilaterally, and a smaller region in middle frontal lobe. It indicates that visual defects in amblyopia can influence the development of white matter.

Published in:

Biomedical Engineering and Informatics (BMEI), 2012 5th International Conference on

Date of Conference:

16-18 Oct. 2012