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The theory of fundamental design limitations is well understood for the case that the performance variable is measured for feedback. In the present paper, we extend the theory to systems for which the performance variable is not measured. We consider only the special case for which the performance and measured outputs and the control and exogenous inputs are all scalar signals. The results of the paper depend on the control architecture, specifically, on the location of the sensor relative to the performance output, and the actuator relative to the exogenous input. We show that there may exist a tradeoff between disturbance attenuation and stability robustness that is in addition to the tradeoffs that exist when the performance output is measured. We also develop a set of interpolation constraints that must be satisfied by the disturbance response at certain closed right half plane poles and zeros, and translate these constraints into generalizations of the Bode and Poisson sensitivity integrals. In the absence of problematic interpolation constraints we show that there exists a stabilizing control law that achieves arbitrarily small disturbance response. Depending on the system architecture, this control law will either be high gain feedback or a finite gain controller that depends explicitly on the plant model. We illustrate the results of this paper with the problem of active noise control in an acoustic duct.