Optimized MR imaging to characterize hyperplastic process in liver tissue

The authors report on a null-point fast inversion recovery (IR) technique that was used to evaluate physiological changes in hepatectomized and sham-operated rats. An increase of signal intensity was observed in resected animals, reaching a peak value 24 h after surgery and returning to baseline preoperative values after two weeks. Sham-operated rats did not show a modification of signal intensity. The results indicate that under suitably chosen parameters, an IR sequence is able to detect and characterize the different stages of a hyperplastic process.<
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