Bioassay — Protocol to layout: A DMFB based implementation

In recent years application of digital microfluidic biochips has largely enhanced biomedical diagnostics procedures with provision for an alternative platform for traditional laboratory methods with miniaturized devices. Such device ensures better precision, higher scalability and integration as well as reconfigurability. In this paper we demonstrated a prespecified bioassay implementation using DMFBs with higher levels of complexity involving simultaneous sample preparation followed by targeted mixing operations. Here we developed efficient methods for architectural level synthesis to obtain optimal scheduling followed by resource binding that formulates effective front end design automation leading to layout in 2D array for bioassay implementation using DMFBs.