Optimized adjustment of single action-potentials to case-specific atrial physiology: Towards clinical implementation

We present a method for modelling case-specific action potentials (APs) based on a simple model for electric wave propagation combined with an optimization procedure that searches the best combination of three model parameter values for a given action potential. The method is applied to a set of 70 APs, showing deviations around 10%. This method can be useful for prognosing possible pathological scenarios of a specific patient, based on data from electrocardiagrams.