Methods of exploring the red blood cells rotation during the simulations in devices with periodic topology

Progress in the development of simulation tools makes it possible to conduct experiments with blood flow containing a large number of solid objects, typically red blood cells (RBC). In our work [2] we designed and verified a set of statistical methods allowing to either confirm or deny the compliance of the behavior of such simulations and real experiments. Rotation (angular speed) of RBC during their movement has proven to be a highly sensitive and precise tool to this exploration. In our article, we compare and confirm the compliance of several methods of measuring and detecting this parameter and its sensitivity to changes in the duration of the experiment. We use Discrete Fourier Transform (DFT) method and rank correlation methods as a key mathematical tool.