Implantable micro CMOS imaging devices for biomedical applications

This paper reviews recent advancement of micro CMOS imaging devices to measure brain neural activities in an un-tethered mouse. Three types of imaging devices have been developed: a fiber endoscope, a head-mountable imaging device, and a brain-implantable imaging device. Among them, a brain-implantable imaging device can realize to observe neural activity in deep brain regions of the brain, such as hippocampus. The detail device structure and characteristics are presented.