A High-Performance Computational Framework for BionetworkAnalysis

We introduce BioGraphE, a general, scaleable integration platform for connecting graph problems in biology to computational solvers and high-performance systems. This framework will enable computational scientists to identify and bring in graph analysis applications and to easily connect them to efficient and powerful computational software and hardware that are specifically designed and tuned to solve complex graph problems. We investigate the use of a Boolean satisfiability solver known as Survey Propagation as a core computational solver and high-performance parallel systems that utilize multithreaded processor architectures.