Adaptive control of multiplexed closed-circuit anesthesia

The design of an adaptive closed-circuit anesthesia controller based on a multiplexed mass spectrometer system is described. The controller deals with measurement deterioration caused by measurement delay and rise time through a long catheter as well as long sampling times due to the multiplexed measurements. Measurement data are extrapolated between sampling periods to increase the estimation convergence rate. A multiple-step-ahead predictive control algorithm is used to calculate intermediate control inputs between sampling intervals. Simulations are used to validate the designed controller.<
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