Voltammetric determination of drugs in complicated multi-component systems

The introduction of foodstuffs, biologically active additives, animal feeds certification procedure requires development of express, high sensitive and accurate methods of determination of a number of chemical organic compounds. Vitamins and some flavonoids belong to alimentary organic substances required in small amounts. The antibiotics contained in foods and biologically active additives based on milk stuffs render toxic activity on human organism. One should pay attention on the high level of contaminating by chloramphenicol, streptomycin, tetracycline -the antibiotics with dangerous side - effects. The optimal conditions of quantitative chemical analysis antibiotics mentioned above, water- and liposoluble vitamins in foodstuffs and feeds, pharmaceuticals (powders, eye drops, tablets etc.) have been determined. The stage of preliminary isolation of determined substances at pretreatment before voltammetric measurements has been considerable simplified. The interference of water-soluble proteins has been eliminated by their hydrolysis, saponification and salting-out with organic solvents and salts. The designed methods allow to control the content of antibiotics, vitamins at levels of the demanded by the normative documents. The methods are certificated.