Investigation of the Electrical properties of Phosphatidylserine Lipid Bilayer Membranes

In this work we investigate the electrical properties of phospholipid bilayer membranes (LBMs) formed from phosphatidylserine by analyzing two experimental setups. The Electrochemical Impedance Spectra (EIS) of phosphatidylserine show that a lipid bilayer membrane formed from this phospholipid has an average specific electrical resistance of 3.466 k Ω.cm
²
and an average capacitance of 0.385 µF/cm
²
. Some of the major factors that affect the LBM resistance include electroporation, the method of deposition, and the surface tension in microchannels for supported LBMs. Therefore, wide apertures remain the most accurate method for supporting LBMs.