Microfluidic-driving multi-function manipulation array of micro-scale biological sample via ac electroosmosis

A microfluidic-driving array is reported in this paper for the multi-function manipulation of micro-scale biological sample based on alternating current electro osmosis flow (ACEOF). The ACEOF manipulation presented in this paper is achieved by the design of the asymmetric pair electrodes array. The features of our proposed microfluidic-driving manipulation actuator can not only orient the micro-scale objects but also convey them. All of microfluidic-driving manipulation actuators are embedded in the device chamber. The functional electrodes are driven by using a waveform generator that provides the sinusoidal wave excitation of only 2 to 10 volts peak to peak. By the control of voltage and frequency applied to manipulation electrodes, the manipulation features of the microfluidic-driven bio-particles can be used for various applications. In this paper, we report the design, simulation and experimental results of this proposed AC electrokinetic manipulation chip.