MLP-GAN for Brain Vessel Image Segmentation

Brain vessel image segmentation can be used as a promising biomarker for better prevention and treatment of different diseases. One successful approach is to consider the segmentation as an image-to-image translation task and perform a conditional Generative Adversarial Network (cGAN) to learn a transformation between two distributions. In this paper, we present a novel multi-view approach, MLP-GAN, which splits a 3D volumetric brain vessel image into three different dimensional 2D images (i.e., sagittal, coronal, axial) and then feed them into three different 2D cGANs. The proposed MLP-GAN not only alleviates the memory issue which exists in the original 3D neural networks but also retains 3D spatial information. Specifically, we utilize U-Net as the backbone for our generator and redesign the pattern of skip connection integrated with the MLP-Mixer [1] which has attracted lots of attention recently. Our model obtains the ability to capture cross-patch information to learn global information with the MLP-Mixer. Extensive experiments are performed on the public brain vessel dataset [2] that show our MLP-GAN outperforms other state-of-the-art methods.