Imaging Breast Ductal Carcinoma In Situ (DCIS) using Pulsed Terahertz Spectroscopy System

This work proposes the use of terahertz (THz) reflection imaging method for investigating breast ductal carcinoma in situ (DCIS). The tumor handled in this work is formalin fixed and paraffin embedded tissue block (FFPE). The goal of this research is to differentiate between DCIS and invasive ductal carcinoma (IDC). In the previous research, THz spectroscopy has shown successful differentiation between cancerous (IDC) and normal breast tissue in freshly excised tumors. The study conducted on IDC has demonstrated interesting signatures in the absorption coefficient of cancer tissues. Similar studies will be conducted in this work for FFPE tissue blocks to investigate the potential invasiveness level of DCIS tumors.