Topical application of Photofrin for photodynamic diagnosis of oral neoplasms

The light-induced fluorescence detection using Photofrin topically provides a sensitive non-invasive technique for the early identification of malignant neoplasms in the oral cavity. The purpose of the study of to evaluate Photofrin with protoporphyrin IX (PPXI) fluorescence as a new diagnostic procedure for the for the detection of hyperplastic and malignant changes of oral tissue.