Synthesis and Characterization of Iron Containing Bioactive Glass for Implants

This work aims to develop a biomaterial for implants with superior antibacterial function, better angiogenesis and rapid osteointegration. For this purpose, 45S5 bioglasses modified by adding different amount of iron oxide (Fe
3
O
4
), from 0 to 8 mol%, were prepared by melt-quenching technique. The structure of the prepared glasses studied by XRD and FTIR showed that the insertion of Fe
3
O
4
do not induce significant changes and thus not affect the beneficial characteristics of the bioglass. Since the electrically polarized bioactive glass and ceramics have been demonstrated to enhance their osteoconductivities, the AC and DC electrical conductivity have been investigated using impedance spectroscopy in the frequency range from 10
²
to 10
⁶
Hz and over the temperature range, 200–400 K. The effects of iron loading on the charge transport mobility were studied. The biocompatibility of the glasses was evaluated in vitro by cell-biomaterial interaction test which show that the glasses are viable for biomedical applications.