NeuroCI: Continuous Integration of Neuroimaging Results Across Software Pipelines and Datasets

Neuroimaging study results can vary significantly depending on the datasets and processing pipelines utilized by researchers to run their analyses, contributing to reproducibility issues. These issues are compounded by the fact that there are a large variety of seemingly equivalent tools and methodologies available to researchers for processing neuroimaging data. Here we present NeuroCI, a novel software framework that allows users to evaluate the variability of their results across multiple pipelines and datasets. NeuroCI makes use of Continuous Integration (CI), a software engineering technique, to facilitate the reproducibility of computational experiments by launching a series of automated tests when code or data is added to a repository. However, unlike regular CI services, our CI-based framework uses distributed computation and storage to meet the large memory and storage requirements of neuroimaging pipelines and datasets. Moreover, the framework's modular design enables it to continuously ingest pipelines and datasets provided by the user, and to compute and visualize results across multiple different pipelines and datasets. This allows researchers and practitioners to quantify the variability and reliability of results in their domain across a large range of computational methods.