Peptide Functionalized Long Period Grating Optical Fibre Sensor for Antibody Measurement with Microfluidic System

A long period grating (LPG) optical fibre sensor modified coated with an Immunoglobulin G (IgG)-binding peptide is reported. The IgG-binding peptide provides a controllable binding affinity towards IgG which is comparable to antibody-antigen interaction due to the non-covalent bonds of the peptide’s amino acid enabling development of a reversible optical fibre immunosensor. A microfluidic system has been developed for reliable flow of liquid over the sensor.