CARLsim 6: An Open Source Library for Large-Scale, Biologically Detailed Spiking Neural Network Simulation

Mature simulation systems for Spiking Neural Networks (SNNs) become more relevant than ever for understanding the brain and supporting neuromorphic computing. The CARL-sim SNN platform is one of the first Open Source simulation systems that utilized CUDA GPUs to address the tremendous parallel processing demands of natural brains. It has evolved over almost a decade in numerous scientific research projects requiring efficient biologically plausible modeling at scale. With its sixth major release, CARLsim 6 respects this legacy by supporting the latest versions of operating systems, development tool chains, multi-core computers, and of course GPUs. It runs on a range of platforms; from Notebooks up to the NVIDIA DGX-A100 supercomputer, and is used in biologically plausible simulations of the hippocampus and neocortex. The latest version has added flexibility for incorporating long-term and short-term synaptic plasticity. Neuromodulation is an important property of neurobiology that can lead to rapid few shot learning, network rewiring, and neural activity modulation. Because of this, CARLsim 6 now supports four multiple neuromodulators for simulating neural excitability and synaptic plasticity.