Measurement of peritoneal fluid absorption and ultrafiltration during peritoneal dialysis using segmental bioimpedance

The aim of this study was to measure intraperitoneal volume (IPV) and ultrafiltration volume (UFV) by monitoring the abdominal resistance using segmental bioimpedance analysis (SBIA, Hydra 4200). Twenty peritoneal dialysis (PD) patients were studied during a fill with 2 L of 2.5% glucose peritoneal dialysate solution. UFV
Drain
(g) was measured as weight difference between fill and drain dialysate volumes. Ultrafiltration volume (UFV
SBIA
; ml) and absorption volume were calculated from the IPV curve derived by SBIA. UFV
SBIA
correlated with UFVDrain (
$\mathrm{R}^{2}=0.98,\,\mathrm{p} < 0.0001$
). This study may provide actionable clinical insights and help clinicians to better understand the function of the peritoneal membrane in individuals. Clinical Relevance—This technique may support personalized medicine by aiding the prescription of PD therapy on a patient-level.