Correlation Between Renal Tracer Parameters Derived for Recognition of Renal Obstruction with 99mTc-DTPA Scintigraphy

Renal obstructions with blockages may be fractional or complete, it affects one side or both sides of urinary system. It progresses speedily (acutely) or gradually (chronically). Renal tracer transit time is important in detecting of renal obstruction levels which is linked with terms like hydronephrosis, Pelvic ureteric Junction (PUJ) obstruction etc. For renal tracer transit time measurements, type of radiotracer like DTPA or MAG3 etc. doesn't matter as all carried through the kidney by urine stream. Assessments of renal function are useful in recognizing the existence of renal disease, monitoring the response of kidneys to medications, and determining the development of renal disease. ^99mTc-DTPA scan helps to differentiate PUJ obstruction from multi-cystic kidney and determine the level of renal obstruction. The objective of this research study was to determine correlation between renal function parameters peak time (Tmax), half time (T1/2) and GFR with ^99mTc-DTPA dynamic renal scintigraphy. For this study, the effects of age, gender, both side of urinary system, stages of obstruction levels of 73 patients were considered and found noticeable correlations among renal function parameters defining presence of hydronephrosis in left and right kidneys called as renal obstructions.