Changes in time-frequency phase spectra vs. ST-segment deviation for detecting acute coronary artery occlusion

The paper deals with a new method for the detection of myocardial ischemia caused by acute coronary artery occlusion, in the early phases. The method is based on the analysis of intra-QRS changes in time-frequency phase spectra generated by a wavelet transform. To verify the method, 11 Langendorff-perfused rabbit hearts have been used. The presented results show that models can detect early ischemia in one of three orthogonal leads as early as one minute after coronary artery occlusion. In addition, the method is compared to the traditional ST-segment analysis.