Adaptive Simultaneous Magnetic Actuation and Localization for WCE in a Tubular Environment

Simultaneous magnetic actuation and localization is a promising technology to realize active wireless capsule endoscopy. In this article, an adaptive approach is proposed to efficiently propel and precisely locate a magnetically actuated capsule in unknown complex tubular environments. In order to track the capsule in real time in a large workspace, we improve upon our previous external sensor-based magnetic localization strategies by proposing an adaptive method to automatically activate an optimal subset of sensors during the capsule movement and developing a simplified multiple objects tracking algorithm to estimate the six-dimensional pose of the capsule in real time. Moreover, based on a study of capsule locomotion in tubular environments with different shapes, we propose to dynamically adjust the pose of the actuator to achieve efficient and robust propulsion of the capsule in an unknown tubular environment. The effectiveness of our proposed system is validated in extensive experiments on phantoms and
ex vivo
animal organs. Compared with the state-of-the-art, our method can realize the closed-loop control of a magnetic capsule without requiring sensing modules to be placed inside the capsule, which can reduce the space constraints and energy consumption of the capsule. Moreover, the system and algorithms for adaptive actuation and localization can provide an improved propulsion speed, workspace range, and localization update frequency as well as a comparable localization accuracy.