Oral Cancerous Cell Detection using Modified Effective Refractive Index Method

Photonic sensing is an upcoming technology with high precision measurements used for bio-sensing applications. In this work, a three-section coupled line photonic crystal structure in the form of a parallel waveguide has been proposed which uses a two dimensional Photonic-Crystal (PhC) sensor. The Modified Effective Refractive Index (MERI) technique is utilized to analyse PhC design using the Meep tool. To study the sensor performance, the analytes chosen were the INOK(Human immortalized normal oral keratinocyte) and the YD-10B(Human oral squamous cell carcinoma). The sensor performance was compared with a Fabry Perot microcavity structure and an appreciable value of Q factor variation was observed. In this report, the proposed sensor has been designed to be presented as a parallel waveguide photonic sensor giving sensitivity around
$1.2\ \mu\mathrm{m}/\text{RIU}$
and Q factor 9517.5 with a cost-effective fabrication profile which is best suited for the biomedical applications.