The Opportunity of Using Platelet Concentrates as an Adjuvant Tool for In-hospital Management of Bone Defects

Bone defects are a frequent, difficult pathology and its clinical management can be quite challenging. The current therapeutic approach “of choice” is the autologous bone transfer, but this procedure is routinely burdened with complications and disadvantages, so an alternative solution, such as using platelet concentrates, has been extensively studied in recent decades. The current article consists of a systematic review of the scientific literature and an epidemiological analysis of data collected from the patients with bone defects who followed a treatment in the County Emergency Clinical Hospital “St. Spiridon”.The results of the review show that platelet concentrates are effective in 91.2% of the subjects included in this study, and the preparation technique is simple and cheap in the case of PRP and especially PRF. Although human subjects accounted for only 1.8%, in all cases, PRF was used and in all cases it proved its effectiveness. The results of the epidemiological study shows 42 patients with bone defects with a mean length of hospital stay of 17 days.In conclusion, platelet concentrates are effective in strengthening bone defects in the in vivo studies, but more studies are needed in human subjects. PRF is easier to prepare, more affordable than PRP and often shows a higher efficiency in bone healing. Since bone defects are a frequently encountered, complicated pathology that requires very high costs and long-term hospitalization, we consider that platelets deserve to be used in the hospital as an adjunct tool in the “fight” with bone defects.