A laser doppler spectroscopy method for laser nanodiagnostics of oncologic diseases

The new method for laser nanodiagnosis of oncological diseases based on the hydrodynamic analysis of nanoparticle distribution in human urine using the laser Doppler spectrometry and self-engineered devices has been proposed, tested and patented for the first time. The generalized distributions of nanoparticles in the urine of a healthy and ill people have been constructed. The statistics on the distribution of nanoparticles in the urine of healthy donors and patients with oncological diseases was collected and added with the results of biochemical analyses of blood and urine of 136 donors in a wide age spectrum. The biochemical analyses were found to correlate with spatial and dimensional distributions of nanoparticles in human urine. The reliability of the diagnosis exceeded 89%, which is a very good result for a simple non-invasive screening method. The results have revealed perspectives for the development of the proposed method for diagnosing a wide range of disorders, such as diseases of heart, liver, kidney and circulatory system. These results provide opportunities and perspectives for further commercialization