Feedback balancing between vaccination and quarantine for disease control: a simulation for COVID-19 in Japan

In this paper, we discuss the balance between two measures to contain infectious diseases. One is isolation of infected individuals. The other is mass vaccination. This paper focuses on shared resources in implementing the two measures in a society. To seek an effective strategy to balance the two measures in the COVID-19 situation in Japan, we propose a mathematical model dividing the population into six subpopulations according to infection, symptoms, and quarantine. Using the data of COVID-19 infections in Japan, parameters in the model are estimated. Based on simulations computed with the model and the estimated parameters, this paper proposes a feedback control that achieves a better balance between isolation and vaccination sharing limited resources.