Water and its Dielectric Signature. New Marker for Biosensing

In this paper we would like to clarify a essential question: "Why is impedance or dielectric spectroscopy sensitive to changes in glucose concentration in blood and why can this be done over a very broad frequency band, including microwaves?" Medical diagnostics would greatly benefit from an answer. Towards this, we want to summarize the underlying physics and base directions towards exploiting this direction. It is our impression that current worldview on the dielectric response of glucose in solution, as outlined below, will support the further evolution of practical noninvasive glucose monitoring solutions.