The use of mm-wave-dielectrometry for the cardio-vascular diseases early diagnostic, therapy and preventive maintenance

Altered activity of the sympathetic nervous system is known to contribute to hypertension via neurohormonal stimulation of adrenergic receptors (ARs), which are members of the guanidine nucleotide superfamily and are divided into some major types. ARs are characterized according to their functional response to their stimulation or inhibition by various substances.Our investigation is devoted to the assessment of molecular mechanisms of transmembrane signal transduction into a cell by means of modeling of these processes under the condition of non-destructive control using the method of dielectrometry combined with traditional technology. The researches of dielectric characteristics in this millimeter wavelength allow to receive unique information about the water component of biosystems. The physical basis is the large difference between a dielectric permeability of biopolymers and bound water and a dielectric permeability of free water, because there is an area of free water dispersion in this range. This method is based on the analysis of conversions of the biopolymer-water matrix owing to conformational conversions of cell macromolecules at the binding of agonists, antagonists and modulators with membrane receptors.