Optical response of photodiode in integrated DNA detection system

This paper describes the fabrication and optical response of photodiodes when they are used in an integrated detection system for DNA analysis. Compared with the traditional approach of external CCD camera based detection systems, the proposed approach can produce a more highly integrated system with higher density. By the use of the natural spectral sensitivity of the photodiode, the need for color filters is eliminated in the integration. Experimental results show that matched and unmatched DNA samples with optical labels can be distinguished by the measured photodiode current when properly excited by optical illumination.